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The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Heat shock protein 27 is more present in the active growth phase of human scalp hair follicles.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Mesenchymal stem cells in people with Hidradenitis Suppurativa are more inflammatory, possibly contributing to the disease.

Hippocampus sparing whole brain radiation therapy prevents hair loss and preserves cognitive function.

Non-immune factors play a significant role in alopecia areata.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Heat treatment increases hair loss in certain mice.

Unroofing is an effective, less invasive, and cost-effective surgery for hidradenitis suppurativa with low recurrence and improved patient quality of life.

The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.

Some children who had stem cell transplants developed permanent hair loss, especially when treated with a drug called busulphan.

The treatment improved hair growth in people with male pattern baldness.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

Acitretin significantly reduced inflammatory attacks in a woman with Naevus Comedonicus Syndrome but caused side effects.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

The research identified 12 antioxidant compounds in Polygonum multiflorum roots, suggesting these as quality markers for the plant's processed roots.

The document concludes that awareness and understanding of hidradenitis suppurativa are increasing, but effective treatments are still needed.

Potassium cyanide treatment changes hair's disulfide bonds, making it more elastic.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

Storing hair follicles in special buffers with added protective substances can increase hair growth and reduce cell death.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.