June 2022 in “Evidence-based complementary and alternative medicine” This study found that acupressure on specific points improved health-related quality of life and reduced total testosterone levels and clinical symptoms in patients with polycystic ovary syndrome compared to controls.
December 2017 in “Journal of Medical Science And clinical Research” This study concluded that adding metformin to oral contraceptives showed no significant improvement in PCOS symptoms compared to placebo, though the PCOS questionnaire was validated for response assessment.
January 2010 in “Springer eBooks” This review discusses the psychological and social challenges of hirsutism in women and suggests that eflornithine cream may offer a small quality of life improvement for affected individuals, though with limited evidence.
August 2008 in “European Neuropsychopharmacology” This study identified significant correlations between self-esteem, psychiatric symptoms, and health-related quality of life in peritoneal dialysis patients.
1 citations
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November 2025 in “International Journal of Dermatology” This study developed the Alopecia Areata Children's Quality of Life Index (AAcQLI) to assess quality of life in children with alopecia areata, demonstrating good reliability and validity in initial tests.
52 citations
,
March 2007 in “Dermatologic Therapy” This article describes the development and validation of a standardized instrument for measuring skin involvement in cutaneous lupus erythematosus, aiming to aid future clinical research and trials.
50 citations
,
December 1998 in “Dermatologic Surgery” In this study, 42% of healthy men aged 18-49 showed moderate to extensive male pattern hair loss, with prevalence increasing significantly with age.
8 citations
,
September 2017 in “The Journal for Nurse Practitioners” This study observed that most women with PCOS in the United States use adaptive coping strategies, while those with higher psychological severity may resort to maladaptive coping methods.
1 citations
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April 2017 in “Drugs & Therapy Perspectives” This review discusses current treatment options for androgenetic alopecia, noting that most lack robust evidence for efficacy and safety, highlighting the need for more comprehensive studies.
January 2026 in “Medico Research Chronicles” In this case study, the researchers at Dr Batra’s® Homeopathy Clinic reported that an individualized classical homeopathic treatment notably improved hair density, thickness, and scalp health, along with enhancing quality of life, in a middle-aged woman with chronic androgenetic alopecia.
February 2017 in “Medicina cutánea ibero-latino-americana” This case report documents an 8-year-old boy with alopecia areata presenting as symmetric alopecic patches with a triangular and targetoid pattern on the scalp, successfully treated with clobetasol propionate foam.
January 2025 in “Advances in Dermatology and Allergology” This study found that the Polish version of the AA-QLI questionnaire is a reliable and internally consistent tool for assessing health-related quality of life in Polish-speaking patients with alopecia areata.
November 2017 in “British Journal of Dermatology” The electronic version of the Dermatology Life Quality Index is as effective as the paper version, with most patients preferring it.
24 citations
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March 2010 in “Value in Health” This review found that the only PCOS-specific quality of life measure, the PolyCystic Ovary Syndrome Questionnaire, has an incomplete development history and lacks some essential measurement properties for clinical trial use.
61 citations
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April 2021 in “Frontiers in Medicine” This study found that hidradenitis suppurativa significantly impaired quality of life in German patients, with severity linked to skin and certain extra-cutaneous changes, but not reduced by surgical or conventional medicamentous treatments.
February 2008 in “Expert Review of Dermatology” This review explores how seborrheic dermatitis impacts patients' quality of life but does not present new research findings; it highlights a need for further studies on influencing factors.
467 citations
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October 2014 in “European Journal of Endocrinology” This paper reviews the diagnostic criteria, etiological factors, and treatment approaches for PCOS, highlighting the importance of considering metabolic issues such as insulin resistance and obesity, but reports no new findings.
238 citations
,
November 2016 in “Journal of The American Academy of Dermatology” In this study, tofacitinib was reported to improve scalp hair regrowth in patients with severe alopecia areata, alopecia totalis, and alopecia universalis, showing a higher response in alopecia areata.
191 citations
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May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.
170 citations
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September 2019 in “Evidence-based Complementary and Alternative Medicine” This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.
144 citations
,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” This review reports that alopecia areata affects about 2% of people globally and is linked with psychiatric and medical comorbidities, highlighting its significant disease burden.
139 citations
,
November 2016 in “Journal of the American Academy of Dermatology” In this retrospective review, tofacitinib treatment was associated with clinically significant hair regrowth in most adolescent patients with alopecia areata, though limitations suggest further studies are needed to confirm these findings.
117 citations
,
February 2017 in “American Journal of Clinical Dermatology” This systematic review concluded that the support for using spironolactone at commonly prescribed doses is based on evidence of limited quality.
66 citations
,
June 2021 in “Journal of The American Academy of Dermatology” In this phase 2 study, baricitinib at 2 mg and 4 mg doses significantly improved hair regrowth in adults with alopecia areata and ≥50% scalp hair loss compared to placebo, without new safety concerns, although the small sample size limits the results' generalizability.
63 citations
,
May 2017 in “American Journal of Clinical Dermatology” This review found that patients with alopecia areata may have lower levels of vitamin D, zinc, and folate, but conflicting evidence precludes definitive clinical recommendations for micronutrient supplementation.
58 citations
,
January 2018 in “International Journal of Women's Dermatology” This review discusses the psychological impact of alopecia on women and reports no new clinical findings, highlighting the effect on self-esteem and quality of life.
55 citations
,
October 2019 in “Dermatology and therapy” This review found that JAK/STAT pathway inhibitors, such as tofacitinib and ruxolitinib, led to symptom improvement in all observed atopic dermatitis cases, but responses were mixed for vitiligo and alopecia areata, with a generally mild safety profile reported.
46 citations
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August 2019 in “Journal of the European Academy of Dermatology and Venereology” This study found that patients with alopecia areata reported worse quality of life and higher anxiety and depression levels compared to those with androgenetic alopecia and healthy controls.
44 citations
,
September 2015 in “Annals of Oncology” This study reported that targeted anticancer therapies are associated with an increased risk of alopecia compared to placebo, although the risk was lower compared to chemotherapy.
43 citations
,
November 2019 in “American Journal of Clinical Dermatology” This review discusses female androgenetic alopecia, highlighting its diagnostic challenges and management strategies, but it reports no new results.