research Evaluation of Hair Follicles as a Surrogate Tissue for Pharmacodynamic Response in Xenograft Tumors
Hair follicles can be used to quickly assess drug effects in cancer treatment.
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research Seasonal Gene Expression Profile Responsible for Hair Follicle Development in Angora Goats
Seasonal changes affect hair growth genes in Angora goats, possibly influencing mohair quality.
research Developmental Mechanisms Controlling Cell Fate Evolution
The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
research Oral Cyclosporin Does Not Arrest Progression of Androgenetic Alopecia
Cyclosporin doesn't stop hair loss.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 NKG2D Lymphocytes in Alopecia Areata Patients
EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.
research Disorders of the Hair and Scalp in Childhood
Childhood hair and scalp disorders can be managed with treatments like cortisone and corticosteroids.
research Personalized Medicine in the Field of Inflammatory Skin Disorders
Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.
research Regulation of Involucrin Gene Expression
Involucrin gene expression is controlled by specific proteins and signaling pathways.
research Cutaneous Permeation And Penetration Of Sunscreens: Formulation Strategies And In Vitro Methods
Effective sunscreen formulations can reduce skin absorption and enhance protection.
research Sex Hormones and Acne: The Role of the Skin as an Endocrine Organ
Sex hormones, especially androgens, play a key role in causing acne.
research Loss of Epidermal Evi/Wls Results in a Phenotype Resembling Psoriasiform Dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research A Review of the Evidence for and Against a Role for Mast Cells in Cutaneous Scarring and Fibrosis
Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
research Comparative Genome Analyses Reveal the Unique Genetic Composition and Selection Signals Underlying the Phenotypic Characteristics of Three Chinese Domestic Goat Breeds
Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.
research Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?
TGase 3 helps build hair structure by forming strong bonds between proteins.
research Hedgehog Signaling Reprograms Hair Follicle Niche Fibroblasts to a Hyper-Activated State
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research Non-Viral Delivery of the CRISPR/Cas System: DNA Versus RNA Versus RNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
research Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling
The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.
research Polycystic Ovary Syndrome and Oxidative Stress: From Bench to Bedside
Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.
research Cosmeceutical Therapy: Addressing the Effects of UVR Photoaging on the Skin’s Circadian Rhythm
Natural skincare products may help reduce sun damage and support the skin's daily cycle.
research Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease
Zebrafish are useful for studying and developing treatments for human skin diseases.
research A Systematic Review of Anti-Aging Effects of 23 Traditional Chinese Medicines
Some traditional Chinese medicines may have anti-aging benefits and could help with hair growth, but more research is needed.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research Efficiency Research of the Comprehensive Hair Loss Treatment
The comprehensive treatment with biomimetic peptide lotion was effective for hair loss.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.
research Repurposing of Various Current Medicines as Radioprotective Agents
Some existing medicines show promise as safe treatments to protect against the side effects of radiation therapy.
research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
research Cell Fate Decisions: Emerging Roles for Metabolic Signals and Cell Morphology
Metabolic signals and cell shape influence how cells develop and change.
research Biochemical Evidence That Small Proline-Rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes
Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.
research The Wnt Inhibitor, Dickkopf 4, Is Induced by Canonical Wnt Signaling During Ectodermal Appendage Morphogenesis
The study found that the protein Dkk4 helps regulate hair growth by controlling Wnt signaling in mice.