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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

PLD is an effective and safer alternative for treating breast cancer.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Hair keratin-associated proteins are essential for strong hair, with over 80 genes showing specific patterns and variations among people.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Nonionic liposomes are the best for delivering genes to skin cells.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

FOXN1 gene variants cause low T cells and immune issues from birth.

Certain drugs that block specific enzymes can help treat prostate diseases.