research Co-Administration of 5α-Reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids
Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.
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research Dual Inhibitors of Urease and Carbonic Anhydrase-II from Iris Species
Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.
research Heat Enhanced Follicular Delivery of Isotretinoin to the Skin
Applying heat with certain chemicals can greatly improve how well isotretinoin gets into the skin through hair follicles.
research Mechanism of Cuticle Hole Development in Human Hair Due to UV Radiation Exposure
UV radiation damages hair by creating holes and peeling cuticle layers.
research Effect of Finasteride Particle Size Reduction on Its Pharmacokinetic, Tissue Distribution, and Cellular Permeation
Smaller finasteride particles increase effectiveness in treating hair loss.
research The Promotion of Hair Regrowth by Topical Application of a Perilla Frutescens Extract Through Increased Cell Viability and Antagonism of Testosterone and Dihydrotestosterone
Applying an extract from Perilla frutescens helps hair grow and fights the effects of hair loss hormones.
research Effect of Miscanthus Sinensis Var. Purpurascens Flower Extract on Proliferation and Molecular Regulation in Human Dermal Papilla Cells and Stressed C57BL/6 Mice
Miscanthus sinensis flower extract may help promote hair growth and prevent hair loss.
research A Comprehensive Review on Phytochemistry and Pharmacological Effects of Stinging Nettle (Urtica dioica)
Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.
research Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth
A complex of 5-aminolevulinic acid and glycyl-histidyl-lysine peptide may help increase hair count in male pattern hair loss without side effects.
research Heterogeneity of Neural Crest-Derived Melanocytes
Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
research Kinetics and Equilibrium of Solute Diffusion into Human Hair
Hair absorbs molecules differently based on their size, charge, and love for water, and less at higher pH; this can help make better hair products.
research Autoimmune Gastritis and Parietal Cell Reactivity in Two Children with Abnormal Intestinal Permeability
Children with autoimmune gastritis showed improved intestinal health over time and should be checked for other autoimmune conditions.
![Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase](/images/research/d91300a7-4d66-4d2c-90ac-293b0dbc5ff5/small/21048.jpg)
research Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase
Compound 15a was effective in inhibiting 5α-reductase.
research Lack of Endocrine Systemic Side Effects After Topical Application of Spironolactone in Men
Topical spironolactone cream doesn't cause hormone-related side effects in the body.
research Specific Interpretation of Hair Concentrations in Two Fatal Metformin Intoxication Cases
Hair analysis showed very high metformin levels in two fatal overdose cases, suggesting it's useful in forensics but sweat may affect results.
research Transcriptome Profiling of Human Follicle Dermal Papilla Cells in Response to Porphyra-334 Treatment by RNA-Seq
Porphyra-334 may help reduce wrinkles and promote hair growth.
research Anti-Inflammatory and Anti-Hyperplastic Effect of Bazhengsan in a Male Rat Model of Chronic Nonbacterial Prostatitis
Bazhengsan reduces inflammation and tissue growth in chronic prostatitis.
research Synthesized Ceramide Induces Growth of Dermal Papilla Cells with Potential Contribution to Hair Growth
Synthetic ceramides may help hair growth by boosting cell growth in hair follicles.
research Eclipta Prostrata Promotes the Induction of Anagen, Sustains the Anagen Phase Through Regulation of FGF-7 and FGF-5
Eclipta prostrata helps hair growth and maintains the growth phase by affecting certain growth factors.
research Screening of Euphorbiaceae Plant Extracts for Anti-5α-Reductase Activity
Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.
research Interconnected Polymers Technology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions
A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.
research Self-Assembled Chitosan Nanoparticles for Percutaneous Delivery of Caffeine: Preparation, Characterization, and In Vitro Release Studies
Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.
research Analysis of Lipids in the Medulla of Japanese Hair and Their Function
Lipids in Japanese hair help maintain glossiness and structure.
research Establishment of an Evaluation Method to Detect Drug Distribution in Hair Follicles
Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.
research Proprietary Herbal Extract Downregulates the Gene Expression of IL-1α in HaCaT Cells: Possible Implications Against Nonscarring Alopecia
A herbal extract may help treat certain types of hair loss by reducing a specific gene's activity.
research Inhibitory Effects of Polyacetylene Compounds from Panax Ginseng on Neurotrophin Receptor-Mediated Hair Growth
Certain compounds from Panax ginseng can block proteins that affect hair growth, potentially helping treat hair loss.
research Evaluation of the 5α-Reductase Inhibitor Finasteride on Reproduction and Gonadal Development in Medaka, Oryzias Latipes
Finasteride negatively affects fish reproduction and gonadal development.
research Discrimination and Proper Use of Polygoni Multiflori Radix, Cynanchi Wilfordii Radix, and Cynanchi Auriculati Radix in Korea: A Descriptive Review
The review suggests renaming two herbs to avoid confusion and recommends more research for safe use.
research LC-MS/MS Improves Screening Towards 21-Hydroxylase Deficiency
LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.
research A Comparative In Vivo and In Vitro Evaluation of Hair Growth Potential of Extracts and an Isolate from Petroleum Ether Extract of Cuscuta Reflexa Roxb
Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.