research Stability Indicating Method Development and Validation of Finasteride by High-Performance Thin-Layer Chromatography Studies
New method effectively analyzes finasteride and its stability.
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research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Tissue Regeneration
ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
research Doxil (Caelyx): An Exploratory Study with Pharmacokinetics in Patients with Hormone-Refractory Prostate Cancer
Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.
research A Method to Improve the Efficacy of Topical Eflornithine Hydrochloride Cream
Using microneedles before applying eflornithine cream can make it more effective at stopping hair growth.
research Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture
Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.
research Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia
Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
research Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation
Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
research Rapid Determination of Finasteride in Human Plasma by UPLC-MS/MS and Its Application to Clinical Pharmacokinetic Study
New method measures finasteride in blood quickly and accurately.
research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Acute and 30-Day Oral Toxicity Studies of a Novel Coccidiostat – Ethanamizuril
Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.
research A Semisynthetic Approach for the Simultaneous Reaction of Grape Seed Polymeric Procyanidins with Catechin and Epicatechin to Obtain Oligomeric Procyanidins in Large Scale
Created large amounts of grape seed compounds using a new method.
research Co-Administration of 5α-Reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids
Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.
research A Comparative In Vivo and In Vitro Evaluation of Hair Growth Potential of Extracts and an Isolate from Petroleum Ether Extract of Cuscuta Reflexa Roxb
Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
research Elucidating the Anti-Aging Mechanism of Si Jun Zi Tang by Integrating Network Pharmacology and Experimental Validation In Vivo
Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.
research Simultaneous Determination of 30 Hormones Illegally Added to Anti-Aging Functional Foods Using UPLC-MS/MS Coupled with SPE Clean-Up
New method effectively detects illegal hormones in anti-aging foods.
research CARI ONE Induces Anagen Phase of Telogenic Hair Follicles Through Regulation of β-Catenin, Stimulation of Dermal Papilla Cell Proliferation, and Melanogenesis
CARI ONE helps start hair growth and makes hair follicles bigger and more numerous.
research Matrix Matching in Quantitative Bioanalysis by LC-MS/MS: A Dream or a Reality?
Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.
research Ichthyosis Fetalis in a Cross-Bred Lamb
A cross-bred lamb with severe skin and movement issues had ichthyosis fetalis but normal vitamin A levels.
research Determination of EtG in Body Hair Samples for Monitoring Teetotalism: A Suitable Alternative to Scalp Hair?
Body hair can be used to test for alcohol intake, especially in men.
research Downstream Molecular Responses to Volatile Signaling in Roots
Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.
research Physiological and Pharmacological Features of the Non-Saponin Components in Korean Red Ginseng
Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.
research Review of Fluconazole Properties and Analytical Methods for Its Determination
Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.
research Assessment of Digital Screen Use by Children and Adolescents During the Pandemic
Children's screen time increased during the pandemic, causing various health issues.
research Human Hair as a Testing Substrate in the Era of Precision Medicine: Potential Role of Omics-Based Approaches
Human hair shows promise for non-invasive medical testing, but more research is needed to standardize its use.
research Determination of Finasteride in Tablets by High Performance Liquid Chromatography
Found accurate way to measure finasteride in tablets.
research Proteomics Demonstration That Histone H4 Is a Colchicine-Induced Retro-Modulator of Growth and Alkaline Phosphatase Activity in Hair Follicle Dermal Papilla Culture
Histone H4, released by cells exposed to colchicine, can cause hair loss by inhibiting cell growth and enzyme activity.
research Development of Validated Methods for the Simultaneous Quantification of Finasteride and Tadalafil in Newly Launched FDA-Approved Therapeutic Combination: Greenness Assessment Using AGP, Analytical Eco-Scale, and GAPI Tools
The study developed accurate, precise, and environmentally friendly methods to measure Finasteride and Tadalafil in a new FDA-approved combination.
research Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry
Method detects finasteride in plasma and semen with high sensitivity and accuracy.
research Determination of Finasteride in Human Plasma by Liquid-Liquid Extraction and High-Performance Liquid Chromatography
Valid method measures finasteride in plasma, simple, fast, and affordable.
research Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.