January 2026 in “International Journal of Applied Pharmaceutics” This study developed a novel LC-ESI-MS/MS method to quantify Minoxidil in pharmaceutical forms, finding it precise, accurate, and robust. It withstands excipient and degradant interference, although Minoxidil degrades under some stress conditions but remains stable thermally.
December 2025 in “Universities Journal of Phytochemistry and Ayurvedic Heights” This study highlights a comprehensive approach for authenticating and assessing the quality of herbal medicines using a combination of physiological, morphological, and molecular techniques, including HPTLC, ICP-MS, UV spectroscopy, and DNA barcoding, to ensure the standardization of herbal medicinal products, particularly Eclipta alba.
February 2024 in “PloS one” This study found that certain nutraceuticals did not interfere with tamoxifen's inhibition of estrogen in breast cancer cells and may enhance its effects, suggesting potential as an adjuvant therapy for hair loss in patients undergoing endocrine therapy.
January 2024 in “Tropical journal of pharmaceutical research” This study found that extracts from Cirsium japonicum var. spinossimum seeds are rich in polyphenols and flavonoids, demonstrating significant anti-inflammatory and cell proliferation effects in specific cell models, suggesting potential as a source for anti-inflammatory and anticancer agents.
January 2024 in “Journal of Natural Remedies” This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.
December 2023 in “Kiểm nghiệm và An toàn thực phẩm/Kiểm nghiệm và An toàn thực phẩm (online)” This study developed a liquid chromatography with tandem mass spectrometry method to detect sex hormones in health supplements from Hanoi, Vietnam, finding three out of 16 samples contained sex hormones, including banned testosterone at low levels (~0.5 mg/kg).
September 2019 in “University of Huddersfield Repository (University of Huddersfield)” In this study, nanoemulsion formulations were found to significantly enhance the skin retention of the antiseptic agent triclosan, with the optimal mixture being a low surfactant concentration, as demonstrated through quantitative and qualitative analysis using tape-stripping and micro CT scans.
January 2017 in “Qucosa (Saxon State and University Library Dresden)” This study found that plasma protein binding significantly contributes to the shifts in glucocorticosteroid concentration ratios among blood, saliva, and hair, challenging prior assumptions about enzyme inactivation as the main factor.
August 2014 in “Acta Crystallographica” This study found that the dissolution profiles of different finasteride polymorphs may affect the quality of finasteride capsules, highlighting the need for polymorphic quality control.
This study found that Chrysanthemum zawadskii extract may promote hair growth by inducing an earlier conversion of telogen to anagen and increasing the proliferation of dermal papilla cells in mice and human hair follicle cultures.
July 2007 in “Journal of Generic Medicines” The UK High Court revoked Lundbeck's patent for Escitalopram, and second medical use claims based on dosage were not considered novel.
October 2006 in “Eclética Química” This study presents three spectrophotometric methods for determining finasteride in bulk and tablet forms, showing a linear relationship between absorbance and finasteride concentration.
June 2004 in “Bulletin of Pharmaceutical Sciences. Assiut University” This study found that among natural hair loss treatments, formulations with Cantharidin in the saponifiable fraction showed superior efficacy compared to those with Pilocarpine.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” This study found that women with PCOS displayed significantly higher activity of 5alpha-reductase, suggesting an additional role for liver and peripheral tissues in their androgen excess.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” This study found that women with PCOS have higher activity of the enzyme 5alpha-reductase, which may contribute to their elevated androgen levels.
January 2000 in “Time to knit” This article describes the extraction and characterization method for wedelolactone from Eclipta alba but presents no new clinical results.
June 2022 in “International journal of drug delivery technology” This study found that Convolvulus arvensis ethanolic extract may promote hair growth and reduce hair loss in albino mice with testosterone-induced baldness by increasing follicular density and the anagen/telogen ratio.
October 2020 in “Journal of Pharmaceutical Sciences” This study found that using gallate-containing formulations like EGCG or tannic acid increased the solubility and controlled release of finasteride in microspheres, enhancing its dermal penetration in pig skin by 10 to 50 times compared to a control.
January 2016 in “International journal of advanced research in chemical sciences” This study developed a new spectrophotometric method to accurately measure finasteride levels in pharmaceutical formulations using a reaction with NBD-CL.
3 citations
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September 2024 in “Journal of Microbiology and Biotechnology” This study found that human placenta hydrolysate effectively inhibited atopic dermatitis development in stimulated human cells and a mouse model, suggesting its potential as a therapeutic agent for related skin diseases.
14 citations
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August 2020 in “Journal of cosmetic dermatology” This consensus report provides detailed recommendations for using Polynucleotides Highly Purified Technology™ in aesthetic skin rejuvenation, highlighting its potential as a biostimulatory booster for face and body revitalization.
667 citations
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May 2008 in “Genes & Development” This review discusses the biochemical and biological functions of histone demethylases and their potential involvement in human diseases, including cancer, but reports no new findings.
522 citations
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January 2001 in “Cancer investigation” This review describes the unique pharmacological profile and clinical applications of pegylated liposomal doxorubicin, emphasizing its role in Kaposi's sarcoma and recurrent ovarian cancer, but reports no new clinical results.
375 citations
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July 2006 in “Journal of Investigative Dermatology” This review discusses the brain-skin connection, the skin's role in stress response, and highlights unmet challenges in understanding stress-induced skin inflammation but reports no new experimental findings.
350 citations
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June 1989 in “The American Journal of Medicine” This study suggests that itraconazole may significantly improve therapy for aspergillosis, with 12 out of 15 evaluable patients responding to the treatment.
349 citations
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January 2005 in “The FASEB journal” This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.
298 citations
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January 2014 in “BioMed Research International” This review discusses various methods for obtaining stem cell-derived conditioned media and its applications in disease treatment, finding generally positive results but highlighting the need for standardized production methods.
282 citations
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April 2007 in “Journal of Agricultural and Food Chemistry” This study found that apple polyphenol extract, particularly oligomeric procyanidins, inhibited pancreatic lipase activity and reduced triglyceride absorption in both mice and humans.
268 citations
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April 2009 in “International Journal of Pharmaceutics” In this study, niosomal formulations enhanced minoxidil skin accumulation compared to commercial and control solutions, suggesting a potential improvement for topical delivery in hair loss treatment.
260 citations
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January 2019 in “Pharmaceutics” This study highlights that niosomes, or non-ionic surfactant based vesicles, offer an advantageous drug delivery system due to their stability, cost-effectiveness, and ability to enhance drug bioavailability and targeting efficiency for various therapeutic agents.