December 2022 in “Archives of Clinical Trials” In this case series study, mild ovarian hyperstimulation syndrome was reported in only one out of 118 PCOS patients receiving highly purified HMG injections for IVF treatment.
April 2017 in “The journal of sexual medicine” This study investigated the effects of 5-alpha-reductase inhibitors on penile histomorphometry in both normotensive and hypertensive rats, reporting no significant changes between treated and untreated groups.
August 2025 in “Journal of Industrial and Engineering Chemistry” A new topical finasteride formulation effectively promotes hair growth with fewer side effects.
July 2026 in “Archives of Dermatological Research” In this study, topical finasteride showed mild-to-moderate improvement in androgenetic alopecia among a cohort in Saudi Arabia, with combination therapy outperforming monotherapy. Adverse events were rare. The study highlights the need for prospective trials to clarify finasteride's standalone effects.
May 2026 in “International Journal of Scientific Research in Chemistry” This study examined finasteride degradation under stress conditions, identifying three unique degradation products in acidic environments, providing insights into impurity profiling and quality control for finasteride formulations.
February 2026 in “Psychoneuroendocrinology” Hair cortisol concentration partly reflects HPA axis regulation but doesn't capture all its complexities.
February 2026 in “Chromatographia” This study used advanced chromatographic and mass spectrometric techniques to develop a method for reliably detecting 17 hair growth compounds in consumer products, aiming to enhance regulatory compliance and ensure consumer safety against illicit compounds.
December 2025 in “Universities Journal of Phytochemistry and Ayurvedic Heights” This study highlights a comprehensive approach for authenticating and assessing the quality of herbal medicines using a combination of physiological, morphological, and molecular techniques, including HPTLC, ICP-MS, UV spectroscopy, and DNA barcoding, to ensure the standardization of herbal medicinal products, particularly Eclipta alba.
August 2025 in “Tropical Journal of Natural Product Research” This study found that hydromethanolic extracts from Carthamus caeruleus L. rhizomes exhibited notable antioxidant and anti-inflammatory effects in both in vitro and in vivo experiments, supporting its traditional medicinal uses and suggesting its potential as a source of therapeutic agents.
June 2025 in “Healthy-Mu Journal” The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.
This study validated an HPLC-UV method to detect minoxidil in cosmetic products and found that 2 out of 9 analyzed products contained minoxidil, despite international regulations banning its inclusion due to potential systemic absorption.
January 2025 in “International Journal of Scientific Research in Science and Technology” This study validated an HPLC analytical method for evaluating fenasteride in commercial products, finding it to be sensitive, selective, and within acceptance criteria for specificity, precision, and stability, making it suitable for quality control testing.
January 2025 in “Revista Vitae” In this study, researchers found that 2 out of 9 analyzed cosmetic hair growth products contained the banned substance minoxidil, demonstrating the presence of this antihypertensive drug in some cosmetics despite regulations.
August 2024 in “Biomedical Journal of Scientific & Technical Research” This review discusses the role of steroid 5 alpha reductase 2 in converting testosterone to DHT and its association with conditions like benign prostatic hyperplasia and prostate cancer; it reports no new results.
February 2024 in “Bioengineering” This study found that a hydrogel formulation containing insulin, chitosan, and hydroxypropyl methyl cellulose improved wound healing in diabetic mice, promoting faster wound closure and organized tissue formation, with in vitro tests showing no cytotoxicity and enhanced cell migration.
December 2023 in “International Journal of Advanced Research in Science, Communication and Technology” This study developed and validated a precise and rapid HPLC method to simultaneously determine Minoxidil and Finasteride in pharmaceuticals, demonstrating successful application for routine quality control without interference from excipients.
December 2023 in “Research Journal of Pharmacy and Technology” In this study, Hibiscus rosa-sinesis flower extract was found to contain 0.33% quercetin according to HPTLC analysis and 0.37% according to HPLC. Heavy metals measured were within acceptable limits, supporting the standardization of the plant material for efficacy and safety testing.
July 2023 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that the E6 gene, but not E7, was responsible for HPV8-induced expansion of keratinocyte stem cells in hair follicle junctional zones in mice.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that HPV8-induced actinic keratoses may mechanistically involve Lrig1+ hair follicle keratinocyte stem cells, with the E6 gene promoting downstream STAT3 activity in a mouse model.
January 2023 in “Brazilian Journals Editora eBooks” HPLC may detect prediabetes and diabetes earlier than Immunoturbidimetry because it shows higher A1c levels.
November 2022 in “Journal of Investigative Dermatology” This study found that human scalp hair follicles produce neurohormones and responded to GHRH stimulation by prolonging hair growth, suggesting a functional peripheral HPS neuroendocrine signaling axis in the skin.
April 2022 in “Molecules” This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.
December 2020 in “Journal of Cosmetic Science” This study determined that caffeine content in anticellulite gels was between 0.7% and 1.7%, and about 1.0% in hair-care products.
August 2018 in “Brock University Digital Repository (Brock University)” This study suggests that the elevated stress hormone response in adolescent male rats may involve increased conversion of testosterone to estradiol at the adrenal cortex level.
This study reported that analyzing hair cortisol levels using a validated online SPE LC-MS method provided a way to assess long-term hormone secretion in 114 healthy volunteers, with a median hair cortisol value of 4.76 pg/mg.
April 2017 in “Journal of Investigative Dermatology” In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.
January 2014 in “Food and Drug” This study established an accurate, reliable, and sensitive HPLC method to detect the illegal addition of minoxidil in herbal hair growth products.
September 2012 in “European journal of psychotraumatology” This study presents a new LC-MS/MS method that allows for more accurate detection of seven steroid hormones in human hair, enhancing the specificity and reliability of hormone analysis in psychoneuroendocrinological research.
January 2012 in “Pharmacy Today” This study concluded that two formulations of finasteride were bioequivalent based on Cmax, AUC, and Tmax data from healthy volunteers.
January 2012 in “CINECA IRIS Institutial Research Information System (University of Genoa)” This study observed fluctuations in hair cortisol levels in rabbits, indicating their HPA axis activity responded similarly to surgical and environmental stressors, suggesting potential anthropomorphic evaluations of stress.