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Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.

Platelet-rich plasma therapy may help treat folliculitis decalvans but benefits might not last without ongoing treatment.

Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.

Iron nanoparticles made from pumpkin extract effectively treated burns and promoted healing in mice.

The study suggests that people with rosacea are more likely to have chronic rhinosinusitis.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

Acne is caused by multiple types of bacteria.

Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Skin fat helps with body temperature control and has other active roles in health.