70 citations,
February 2019 in “The journal of immunology/The Journal of immunology” Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.
68 citations,
February 2015 in “Journal of the European Academy of Dermatology and Venereology” Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.
68 citations,
May 2011 in “European Journal of Dermatology” Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
59 citations,
July 2015 in “Journal of Immunology” Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
53 citations,
November 1992 in “Mayo Clinic Proceedings” HIV can cause unusual and severe skin problems that are hard to treat.
48 citations,
April 2010 in “Journal of the European Academy of Dermatology and Venereology” Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
44 citations,
October 2017 in “British Journal of Dermatology” Botulinum toxin has potential for treating various skin conditions and improving wound healing.
42 citations,
April 2021 in “Journal of clinical pharmacology” Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
42 citations,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
39 citations,
May 2004 in “Clinics in Dermatology” The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.
38 citations,
July 2010 in “Clinical, cosmetic and investigational dermatology” To treat tinea capitis in children, oral antifungal medication is necessary, with newer drugs offering shorter treatment times than the traditional griseofulvin.
27 citations,
July 2012 in “Dermatologic Surgery” Higher caspase-1 levels found in balding scalps; reducing it may help treat hair loss.
25 citations,
July 2014 in “Hong Kong medical journal” Some skin disorders might be linked to H. pylori infection, but more research is needed to confirm this.
24 citations,
May 2021 in “Nature Communications” Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.
24 citations,
January 2019 in “Biomaterials Science” The shape of fibrous scaffolds can improve how stem cells help heal skin.
22 citations,
April 2020 in “Scientific reports” Changthangi goats have specific genes that help produce Pashmina wool.
21 citations,
January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
21 citations,
March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
21 citations,
April 2010 in “Molecular Medicine Reports” Zinc supplementation may help improve treatment outcomes for chronic hepatitis C.
20 citations,
September 2020 in “Journal of Translational Medicine” Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
20 citations,
November 2019 in “Current Opinion in Systems Biology” The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
19 citations,
June 2007 in “Veterinary Dermatology” Amitraz effectively treated sarcoptic mange in three alpacas.
16 citations,
March 2018 in “Seminars in Oncology” The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
15 citations,
August 2006 in “Journal of Cutaneous Pathology” HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
11 citations,
October 2018 in “Nucleic Acid Therapeutics” Modified KGF mRNA helps skin cells grow and move faster, which may improve wound healing.
11 citations,
March 2018 in “Protoplasma” Lipopolysaccharides boost wheat seedling growth, but procyanidin B2 weakens this effect.
9 citations,
May 2021 in “Immunological Reviews” Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
9 citations,
March 2015 in “International reviews of immunology” Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.
6 citations,
December 2020 in “Dermatological reviews” COVID-19 may worsen with androgens; anti-androgen drugs could help.
6 citations,
June 2019 in “Biotechnology Letters” Gene therapy shows promise for improving wound healing, but more research is needed for human use.