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The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

An imbalanced gut and lack of biotin can cause hair loss in mice.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

New treatments for male hypogonadism are effective and should be personalized.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Testosterone may slow down wound healing and increase inflammation.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Spironolactone plus finasteride reduces hirsutism more effectively.

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

CLE40 and CRN/CLV2 pathways have opposite effects on root growth in Arabidopsis.

Cysteine helps maintain keratin production in skin cells even when iron is low.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.