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Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Human scalp hair follicles can produce hormones and have a system similar to a brain-body communication network.

Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.

5-Alpha Reductase Inhibitors are effective for male hair loss and some skin conditions, but their effectiveness in women and safety concerns require careful use.

A mix of Polygonatum sibiricum and Nelumbinis semen may ease menopause symptoms with fewer side effects.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

High mTORC1 activity slows hair growth and causes it to lose color.

Quercetin may help improve symptoms of polycystic ovary syndrome.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

Pregnant women with PCOS have higher levels of Neurokinin B in the placenta, especially with female babies.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.

Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

Certain drugs can worsen hair loss in people prone to androgenetic alopecia.