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Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Equisetum debile extracts may help with skin whitening, anti-wrinkle, and anti-hair loss treatments.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.

New therapies are being developed that target integrin pathways to treat various diseases.

Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.

Blue light can help treat skin conditions like eczema and acne without major side effects.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Scalp cooling is an effective way to prevent hair loss from chemotherapy.

Preventive measures and effective management are crucial for reducing skin side effects in cancer treatment.

Many women with hair loss also have thyroid issues, high blood pressure, and low Vitamin D.

Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.

Microbial biosurfactants could be a safer and environmentally friendly alternative to chemical surfactants in cosmetics.

The true incidence of post-Finasteride syndrome is unclear, and more research is needed.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Low Vitamin D receptor levels in breast cancer are linked to worse outcomes and more bone metastases, and could be a marker for prognosis.

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.