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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgens can both increase and decrease hair growth in different parts of the body.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Zinc is effective for treating various skin conditions, including warts and acne.

PRP injections increase hair density and satisfaction in androgenetic alopecia patients.

Low iron levels may be linked to some types of hair loss in women.

The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

A new gene, JMJD1C, may affect testosterone levels in men.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.