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Hormones and signaling pathways control sebaceous gland function and could help treat acne.

Birth control pills can improve or cause acne and hair issues, with improvements more common, and may affect skin pigmentation.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Melatonin affects mouse skin and may regulate skin functions.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Aromatase inhibitors cause male pattern hair loss in women.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.

The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.

Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Hair color is determined by melanin produced and transferred in hair follicles.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Compound 15a was effective in inhibiting 5α-reductase.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Lower SHBG levels may increase the risk of PCOS.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.