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All women with Polycystic Ovary Syndrome (PCOS) in a study had at least one skin disorder, with the most common being excessive hair growth, acne, dark skin patches, hair loss, and oily skin.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

An imbalanced gut and lack of biotin can cause hair loss in mice.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.

Testosterone may slow down wound healing and increase inflammation.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.

IGF-1 increases whisker growth in transgenic mice.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Male hormones worsen kidney transplant damage, but blocking them helps.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

Finasteride helps treat hair loss by blocking enzyme activity.