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Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.

The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.

Vitamin D is important for skin health and can help treat and prevent various skin conditions.

FGF21 can help reduce skin inflammation caused by C. acnes.

Sox2 controls hair color by affecting pigment production in hair follicles.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Interleukin-1 increases keratin K6 production in skin cells.

Platycladus orientalis leaf extract helps hair grow by activating certain proteins.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

Urinary Se to creatinine ratio, serum Se, and glutathione peroxidase are effective early biomarkers for selenium status in dogs.

Hairless protein affects hair follicle structure by regulating the Dlx3 gene.

JAK inhibitors show promise for treating various skin diseases.

Excessive hair growth in women can be harmless or signal serious health issues, and treatment often includes medication and hair removal, with noticeable results after 3-6 months.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.

A specific gene variation is linked to a higher risk of polycystic ovary syndrome in Caucasian women.

17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

RNA from horse hair follicles can track circadian rhythms non-invasively.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Finasteride may cause kidney damage.

Estrogen helps prevent artery plaque by stopping monocyte capture in blood vessels.