46 citations,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
40 citations,
April 2014 in “Genes & Development” Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
39 citations,
March 2018 in “Archives of Dermatological Research” Androgens may block hair growth signals, targeting this could treat hair loss.
32 citations,
September 2018 in “Clinical Obstetrics and Gynecology” Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
25 citations,
September 2020 in “Molecules” Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
24 citations,
November 2015 in “Annals of Nutrition and Metabolism” Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.
18 citations,
October 2014 in “Experimental Biology and Medicine” Eating vitamin A affects hair growth and health by changing cell signals in mice.
15 citations,
August 2020 in “American Journal of Pathology” Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.
14 citations,
June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
13 citations,
October 2017 in “Bioscience, Biotechnology, and Biochemistry” Centella asiatica extract may help promote hair growth by blocking a specific cell signaling pathway.
9 citations,
May 2019 in “Experimental Cell Research” HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
7 citations,
October 2015 in “American Journal of Primatology” Monkeys with hair loss during pregnancy showed higher stress hormone levels and invested differently in their offspring.
5 citations,
January 2021 in “Biomedicine & Pharmacotherapy” Policosanol helps treat hair loss by balancing hormones and supporting hair growth.
3 citations,
April 2019 in “Hormone and Metabolic Research” Women with PCOS have lower adiponectin hormone levels and are more likely to have insulin resistance.
September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
October 2021 in “Research Square (Research Square)” Hair follicle stem cells in hairpoor mice are disrupted, causing hair loss.
April 2019 in “Journal of Investigative Dermatology” Calcium signals and SHH guide the direction of feather growth in chicken skin.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.
April 2021 in “Journal of Investigative Dermatology” Transgender patients on hormone therapy experience more acne and hair loss, but less skin inflammation.
271 citations,
September 2008 in “Nutrition reviews” Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.
139 citations,
August 2018 in “Development” The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
72 citations,
October 2009 in “The FASEB journal” TRH stimulates human hair growth and extends the hair growth phase.
71 citations,
June 2006 in “Human Reproduction” Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.
68 citations,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
65 citations,
July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
58 citations,
November 2020 in “International Journal of Molecular Sciences” SHBG may be a useful early indicator and treatment target for PCOS.
36 citations,
November 2018 in “BMC plant biology” ROXY proteins help plants respond to nitrate shortage by affecting nutrient sensing and growth.
36 citations,
July 2011 in “Journal of The American Academy of Dermatology” People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.
20 citations,
September 2013 in “Anti-Cancer Drugs” PTH-CBD could help prevent and treat hair loss caused by chemotherapy in mice.