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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Finasteride cream reduces hair growth in women with hirsutism, but more research needed.

Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Women with mild acne are more likely to have polycystic ovary syndrome (PCOS) than those without acne.

Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.