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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

The 39th Manfred Donike Workshop discussed methods for detecting misuse of steroids, gene doping, and the complexity of identifying drug residues in urine, highlighting the ongoing efforts to improve global anti-doping work.

A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.

Early-onset male baldness may increase the risk of metabolic syndrome.

The document concludes that transsexual individuals often experience improved quality of life after transitioning, despite higher risks of psychiatric issues and mortality.

Transgender treatment includes hormones and surgery, but long-term effects are unknown and counseling is needed.

People with alopecia areata often have abnormal thyroid hormones, thyroid antibodies, antinuclear antibodies, low vitamin D, and high C-reactive protein levels.

Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Early detection of ovarian steroid cell tumors is crucial to prevent lasting symptoms.

A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Pharmacists should interpret lab data and perform physical exams to improve patient care.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Parathyroid hormone-related protein helps control hair growth phases in mice.

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

Thyroid function may influence hair loss after COVID-19.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

The method effectively identifies banned substances in hair loss and skin disease cosmetics.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.