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Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Neurosteroids show promise for treating epilepsy and more research is needed.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.

Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Adrenal disorders can cause lasting brain and behavior issues in children.

Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Finasteride may increase depression by reducing brain cell growth.

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Serenoa repens and N-acetyl glucosamine/milk proteins complex may help with hair growth and prevent hair loss.

Marine-derived ingredients show potential for hair health but need more human trials to confirm effectiveness.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Auxin and ethylene hormones both work together and against each other to control plant growth.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.