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Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Five new mutations in the androgen receptor gene were found, helping to understand androgen insensitivity syndrome better.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Finasteride can reduce fertility in some men, but stopping it increases sperm count.

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Different hormones affect hair growth and conditions, with some causing hair loss and others promoting it.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

A woman with acromegaloidism and normal growth hormone levels had a rare X-Tetrasomy, suggesting a need to study X-chromosome genes for their role in growth and facial development.

Some people have genetic mutations that make them resistant to vitamin D, leading to rickets even with enough vitamin D intake.

Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Lower SHBG levels may increase the risk of PCOS.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.