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The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Alopecia patients have less GPER-1, which might affect hair loss.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Testosterone therapy increases bone density in older men with low testosterone levels.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Testosterone's muscle-building effects do not require its conversion to DHT.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

A new gene, JMJD1C, may affect testosterone levels in men.

New treatments for male hypogonadism are effective and should be personalized.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.