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This article discusses the complex pathogenesis of hirsutism and reports no new clinical results; further research is needed for better diagnostic and therapeutic strategies.

This study found that obesity in PCOS women with biochemical hyperandrogenemia lowers androstenedione levels and increases the testosterone to androstenedione ratio, but this was not observed in women with clinical hyperandrogenemia or in controls.

This study found that among older men, lower calculated free testosterone was significantly associated with a higher risk of heart failure, suggesting a possible role of testosterone deficiency in heart failure incidence.

This study highlights that lower testosterone in men and higher testosterone in women are linked to increased risks of metabolic syndrome and type 2 diabetes, with associated skin diseases indicating potential cardiovascular complications.

This study found that women with female pattern baldness had a marked increase in the 3α,17β-androstanediol glucuronide/sex hormone binding globulin ratio and low serum sex hormone binding globulin.

This study found that both cyproterone acetate alone and combined with ethinyl oestradiol reduced androgen levels and slightly increased SHBG binding in women with hirsutism, but showed no difference in hair regrowth rate between the treatments.

This study found that in women with PCOS, suppressive therapy using spironolactone plus oral contraceptives improved hirsutism more effectively than either treatment alone, with initial scores predicting success.

This study found that in men with sexual dysfunction, use of 5ARI may reduce sexual drive and spontaneous erections without worsening pre-existing erectile or ejaculatory issues.

This review evaluates the hormonal, metabolic, and clinical aspects of a male equivalent PCOS syndrome in men and highlights areas where further research is needed, reporting no new empirical findings.

This study suggests that some men with premature androgenic alopecia may have hormonal profiles similar to women with polycystic ovary syndrome, potentially indicating a male equivalent of the condition.

This study found that combining oral testosterone with dutasteride increased testosterone bioavailability in hypogonadal men while suppressing dihydrotestosterone levels over a 28-day period.

This study found that the combination of ethinylestradiol and desogestrel significantly decreased hair growth and hormone levels in hirsute women, suggesting a relationship between hormone changes and treatment effectiveness.

This review discusses hormonal changes during menopause, emphasizing the relative androgen excess and the role of insulin resistance, and reports no new clinical findings.

In this study, 12 months of cyproterone acetate and ethinyl oestradiol treatment significantly reduced hair growth rate and certain hormone levels in hirsute women, though hair density and prolactin levels remained unchanged.

This study suggests that hepatocellular carcinoma in cirrhotic men is associated with altered sex-steroid metabolism, indicated by lower testosterone and 5 alpha-dihydrotestosterone levels compared to cirrhosis alone.

This study found that overweight women with polycystic ovary syndrome carrying the HSD3B1 1245C allele had an increased presence of female pattern hair loss compared to those with the wild-type genotype.

This study found that male pattern baldness may serve as a clinical marker for circulating sex hormone levels in men with localized prostate cancer, while chest hair density showed no significant hormone association.

This study found that an oral testosterone formulation normalized serum testosterone levels and significantly reduced SHBG in men with experimentally induced hypogonadism after nine days of treatment, suggesting potential efficacy for testosterone deficiency.

This report describes a possible case of burn-induced bullous pemphigoid, as the disease was transient and did not recur, suggesting a potential link between burns and the condition.

This study found that triglycerides, testosterone, and SHBG levels were associated with hyperandrogenism in women with PCOS, while FGS was not linked to this condition.

This study found that women with polycystic ovary syndrome in China had elevated androgen levels compared to healthy controls, and suggests body weight management and SHBG and FAI testing are recommended for these women.

In this study, researchers reported that the SHBG +5790 G>A polymorphism was associated with an increased risk of developing resistance to hormonal castration in advanced prostate cancer patients.

In this study, the free androgen index (FAI) was found to be a reliable marker for diagnosing and monitoring adolescent girls with hyperandrogenism, suggesting clinical reference values for PCOS, obesity, and idiopathic hirsutism.

In this review and meta-analysis, the authors concluded that 5α-reductase inhibitor therapy is not consistently associated with significant increases in serum testosterone levels in men.

This study suggests that 5-ADIOL-S may contribute to the synthesis of potent androgens in peripheral tissues, and 3 alpha-DIOL-S could be a marker of androgen metabolism in various female patient groups.

In this study, hirsute women treated with cyproterone acetate and ethinyloestradiol experienced significant reductions in sebum secretion and hair growth after several months.

This study found that an 8-week supplementation with specific probiotic strains improved hormonal markers and oxidative stress while decreasing inflammation in women with PCOS, although clinical symptoms like acne and hirsutism showed no significant improvement compared to the placebo group.

This study found that curcumin lowered fasting blood sugar levels and improved menstruation characteristics in women with polycystic ovary syndrome, but it did not affect other metabolic, hormonal, or hirsutism indices.

The researchers reported a high incidence of hyperuricemia in women with PCOS, with positive correlations to testosterone, SHBG, HOMA-IR, and LDL levels, but negative correlations to HbA1C, FPG, and FSI.

This study suggests that perforin/granzyme-B might play a role in the interaction of sex hormones in patients with polycystic ovary syndrome.