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Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Testosterone's muscle-building effects do not require its conversion to DHT.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Mutant mice help researchers understand hair growth and related genetic factors.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Testosterone may slow down wound healing and increase inflammation.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Key genes are crucial for Drosophila wing development and could be insecticide targets.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.