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Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

A neglected leprosy treatment led to rare scalp hair loss in an Indian woman, which improved with proper medication.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.

Skin issues are common and important for diagnosing PCOS.

Androstenedione is better than testosterone for diagnosing PCOS in Indian women.

Hair analysis can somewhat track past testosterone levels but is influenced by factors like hair washing, growth rate, sex, and hair color.

A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.

ROS may affect hair loss related to hormones.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.