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The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Finasteride helps hair growth but may cause sexual side effects.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Heavily hunted wolves have higher stress and reproductive hormone levels.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

Oriental herbal medicine with moxibustion may improve pregnancy rates and other symptoms in PCOS, but more high-quality research is needed.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

A woman with Parkinson's disease experienced hair loss from the Parkinson's medication pramipexole, which improved after stopping the drug.

Alopecia areata leads to significantly higher healthcare costs due to more doctor visits and prescriptions.

Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.

Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.

Hsc70 protein may influence hair growth by responding to androgens.

The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.

Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Beard hair loss can signal early diabetes and thyroid issues, treatable with specific cream.