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March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
506 citations,
January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
288 citations,
June 2009 in “Human reproduction update” The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.
270 citations,
April 2007 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.
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June 1975 in “Journal of Steroid Biochemistry” Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
226 citations,
September 2001 in “Journal of The American Academy of Dermatology” Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.
222 citations,
January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
219 citations,
March 2004 in “Journal of The American Academy of Dermatology” 5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.
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November 2015 in “The Lancet HIV” PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.
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July 2001 in “Journal of The American Academy of Dermatology” Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.
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May 2014 in “The Journal of Sexual Medicine” Hormone therapy for trans individuals is effective and generally safe in the short term.
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July 2011 in “Cochrane library” Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.
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April 1994 in “Clinical endocrinology” Androgens can cause hair growth in some areas and hair loss on the scalp.
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Androgenetic alopecia in women needs more research and better management strategies.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
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January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
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October 2007 in “Clinical Interventions in Aging” Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
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November 2009 in “Human Reproduction” Women with PCOS and higher androgen levels are more likely to have fatty liver disease.
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December 2013 in “The Journal of Pediatrics” Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
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November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
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April 1999 in “The Journal of Clinical Endocrinology and Metabolism” Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.
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December 2013 in “International Journal of Dermatology” The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.
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May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
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June 2011 in “Journal of The American Academy of Dermatology” 5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.