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Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

Kimchi probiotics slightly improved hair density, but more research needed.

Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.

Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Understanding hair follicle structure is key for treating hair disorders and could help develop new treatments.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

Androgens can both increase body hair and cause scalp hair loss.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

AGA in children needs careful diagnosis due to low androgen levels and possible other causes.

Sardinians were historically short due to a mix of genetics and factors like disease and poor nutrition, but recent height increases suggest better living conditions had a bigger impact.

Hair loss can cause serious mental health problems and treating it requires a team of experts.

Pregnancy can cause unique skin issues, some of which may risk the mother and baby's health and need careful treatment.

The document concludes that scalp disorders can be treated with hair washing, specific shampoos, medications, and sometimes surgery or hair transplants, but hereditary baldness is untreatable.

The document reports three sisters with Woodhouse-Sakati syndrome showing typical symptoms and unusual gynecological anomalies.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

Most types of hair loss can regrow naturally, but there are no effective cures for male pattern or age-related hair loss, and only limited options for females.

Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.

Intravenous calcium therapy is a safe and effective treatment for a rare type of rickets.

PCOS and related metabolic issues often run in families.

Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.

Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.