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Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Lower SHBG levels may increase the risk of PCOS.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Minoxidil helps hair regrowth in alopecia patients, with 16 having good results and no side effects.

Vitiligo affects overall health and self-esteem, needing more research and awareness.

Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Advanced human skin models improve drug development and could replace animal testing.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Early diagnosis and treatment of discoid lupus erythematosus improve outcomes.

Acne keloidalis nuchae is a tough-to-treat condition that greatly affects quality of life, especially in men of African descent.

Both mouse and rat models are effective for testing alopecia areata treatments.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Early balding linked to higher heart disease risk.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.