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    Glossary Holocrine Secretion

    cells disintegrate to release their contents

    Holocrine secretion is a process where entire cells disintegrate to release their contents. This type of secretion is seen in sebaceous glands of the skin, where the cells burst to release sebum, an oily substance that helps lubricate and protect hair and skin.

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    Research 30 of 148

    1. Beyond acne: Current aspects of sebaceous gland biology and function Reviews in Endocrine and Metabolic Disorders · 2016 · 97 citations
    2. Lipid droplets and associated proteins in sebocytes Experimental Cell Research · 2015 · 24 citations
    3. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2022
    4. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2021
    5. Comparative Characterization of Human Meibomian Glands, Free Sebaceous Glands, and Hair-Associated Sebaceous Glands Based on Biomarkers, Analysis of Secretion Composition, and Gland Morphology International journal of molecular sciences · 2024
    6. Comparative Histological Study of the Sebaceous and Sweat Glands Between the Gray Mongoose (Herpestes edwardsii) and the Domestic Cat (Felis catus) Kerbala Journal of Veterinary Medical Sciences · 2026
    7. Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands Molecular and Cellular Biology · 2014 · 36 citations
    8. The regeneration of caudal epidermal specializations inLygodactylus picturatus keniensis (gekkonidae, Lacertilia) Journal of Morphology · 1971 · 26 citations
    9. Ligand‐independent epidermal growth factor receptor hyperactivation increases sebaceous gland size and sebum secretion in mice Experimental Dermatology · 2013 · 22 citations
    10. Regeneration of Human Scar Tissue with Topical Iodine: A Preliminary Report—Part 2 2008 · 1 citations
    11. Genetic and histological correlation between the musk gland and skin of Chinese forest musk deer bioRxiv (Cold Spring Harbor Laboratory) · 2022
    12. Adipose tissue remodeling via TSLP-mediated IL-4/IL-13 signaling: Implications for atopic dermatitis and skin barrier Journal of Allergy and Clinical Immunology · 2024
    13. A Comprehensive Review: The Bidirectional Role of Sebum in Skin Health Bioengineering · 2025
    14. Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis 2023
    15. Regional difference in sebum production by androgen susceptibility in human facial skin Experimental Dermatology · 2013 · 14 citations
    16. Histology, lectin histochemistry and ultrastructure of interdigital gland in crossbred sheep 2020 · 3 citations
    17. Histomorphology and Chemical Constituents of Interdigital Gland of Vembur Sheep, Ovis aries Veterinary sciences · 2022 · 2 citations
    18. An updated review of the sebaceous gland and its role in health and diseases Part 1: Embryology, evolution, structure, and function of sebaceous glands Dermatologic Therapy · 2020 · 13 citations
    19. A practical guide for the study of human and murine sebaceous glands <i>in situ</i> Experimental Dermatology · 2013 · 56 citations
    20. Influence of substance-P on cultured sebocytes Archives of Dermatological Research · 2008 · 46 citations
    21. Effect of dihydrotestosterone on the upregulation of inflammatory cytokines in cultured sebocytes Archives of Dermatological Research · 2009 · 32 citations
    22. Hidradenitis suppurativa: an-androgen-dependent disorder British Journal of Dermatology · 1986 · 49 citations
    23. Distribution of 1,25-dihydroxyvitamin D3[22-oxa] in vivo receptor binding in adult and developing skin Archives of dermatological research · 1995 · 15 citations
    24. Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 2 citations
    25. Stress-related skin disorders Reviews in Endocrine and Metabolic Disorders · 2016 · 67 citations
    26. Pharmacologic Modulation of Sebaceous Gland Activity: Mechanisms and Clinical Applications Dermatologic Clinics · 2007 · 30 citations
    27. Skin diseases in consequence of endocrine alterations The Aging Male · 2006 · 16 citations
    28. Sebum Production Springer eBooks · 2016 · 1 citations
    29. Skin aging: mechanisms, evaluation, and rejuvenation The EMBO Journal · 2026
    30. Wnt Signaling in Skin Development, Homeostasis, and Disease Cold Spring Harbor Perspectives in Biology · 2012 · 260 citations