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The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

HOXC13 is essential for hair and nail development by regulating Foxn1.

The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.

Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.

A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.

Stress hormones and autoimmune reactions can cause hair loss.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Finasteride can reduce fertility in some men, but stopping it increases sperm count.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.

Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.

Polyamines help fix DNA damage accurately in cells.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Lichen planopilaris (LPP) is linked to androgen excess, while frontal fibrosing alopecia (FFA) is linked to androgen deficiency.

The HoVert technique is a simple, cost-effective new method that improves alopecia diagnosis by allowing detailed analysis from a single biopsy.

Hoxc genes control hair growth through Wnt signaling.

The article suggests using four questions to tell apart necessary medicalization from excessive medicalization, focusing on problem significance, social expectations, medical understanding, and effective resolution.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.

The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.