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This article reviews idiopathic hirsutism, focusing on its definition, diagnosis, causes, and treatment options, without presenting new clinical findings.

This study found that administering human amniotic mesenchymal stem cells (hAMSCs) in a mouse model of psoriasis improved skin lesions and reduced inflammation-related markers, suggesting potential therapeutic benefit and safety for treating psoriasis, and identified specific gene targets involved in the treatment's mechanism.

This study found that anionic HSES achieved high complexation efficiencies with various steroids, significantly enhancing their solubility, while specific β-cyclodextrin thioethers showed selective binding to testosterone and estradiol.

This study validated the HS 3D-SeboSkin model as a reliable tool for preclinical research, effectively preserving the structure and biomarker expression of lesional and perilesional HS skin ex vivo.

The correspondence discusses the higher prevalence of acne vulgaris in hidradenitis suppurativa patients, but notes potential overestimation due to unrecognized facial HS.

This article reviews the challenges in treating hidradenitis suppurativa and discusses potential treatment options, emphasizing the need for increased awareness and comprehensive care, but reports no new clinical results.

This review discusses the molecular mechanisms of Hutchinson-Gilford progeria syndrome and evaluates current research trends, available mouse models, and prospects for developing therapies, but reports no new clinical findings.

This report highlights that the ISHRS website achieved 1,000,000 active users in 2025, signaling its emergence as a leading global resource for hair restoration information.

This source reports that a study by Liu et al. analyzed genetic factors influencing adalimumab response in hidradenitis suppurativa, finding a specific genetic variant (SNP rs59532114) associated with an inadequate response to the treatment due to increased abscess and inflammatory nodule counts.

This case report describes an instance of autosomal recessive uncombable hair syndrome caused by maternal uniparental disomy of chromosome 1.

This review discusses current treatments and management strategies for hidradenitis suppurativa, noting the mixed effectiveness of various therapies, including surgery, antibiotics, and hormonal treatments, but reports no new clinical findings.

This article discusses how activating the hexosamine pathway may enhance skin homeostasis by increasing hyaluronic acid secretion and supporting hair follicle stem cell self-renewal, but reports no new results.

This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.

This paper reviews hidradenitis suppurativa, comparing its clinical and histopathological characteristics to acne, questioning the proposed link to terminal hair follicles, and reports no new results.

Elderly patients have more severe hidradenitis suppurativa and may need different treatments.

This study found that Hibiscus rosa-sinensis leaf extract promoted hair growth in rats more effectively than its flower extract, suggesting its potential as a natural alternative for hair growth treatments.

This article reviews the pathophysiology of hidradenitis suppurativa and suggests that a complex interplay of genetic, immunological, and biomechanical factors contributes to the condition, but presents no new clinical findings.

This case study reports significant clinical and hormonal improvement in a 21-year-old woman with HAIR-AN syndrome after nine months of treatment with oral contraceptives and spironolactone.

This study identified two novel mutations in the CDH3 gene causing HJMD in a Chinese patient, expanding the genetic and phenotypic understanding of the disorder.

This study found that hair follicle stem cells from hidradenitis suppurativa patients showed alterations in cell cycle regulation and DNA replication, potentially linking genetic predisposition to the skin inflammation characteristic of the disease.

This case report describes a child with Gomez–Lopez–Hernandez syndrome, highlighting developmental challenges and medical interventions, yet noting academic success and participation in mainstream activities.

The document explains that hirsutism, often caused by hormonal issues, can be managed with treatment to improve both physical appearance and mental health.

This study suggests that impaired Nrf2 signaling and its relationship with keratin 16 may contribute to follicular hyperkeratinization and occlusion in hidradenitis suppurativa, opening new therapeutic avenues.

This study suggests that heparan sulfate is crucial for regulating hair follicle formation, cycling, and gland morphogenesis, with its ablation leading to continuous hair growth and increased gland activity in mice.

This study found that knocking out the Hars2 gene in mouse cochlear hair cells led to mitochondrial dysfunction and ROS stress, resulting in progressive hearing loss and differential effects on inner and outer hair cells.

This case study describes a 19-year-old female with hidradenitis suppurativa whose symptoms and metabolic abnormalities improved significantly over 3 years on a combined regimen, though some skin lesions persisted.

This study found that activating the hexosamine pathway increased hyaluronic acid secretion and hair follicle stem cell numbers in vitro, suggesting its role in modulating skin homeostasis.

This article argues that a proposed merger between ISHRS and AACS would be detrimental to the ISHRS, but it presents no new research findings.

This study observed that spironolactone improved hidradenitis suppurativa in over 80% of female patients at 3 and 6 months, with no significant differences in response due to menstrual flares or polycystic ovarian syndrome, but mild adverse events were reported.

This study found that laser hair removal effectively reduces disease severity in hidradenitis suppurativa with minimal side effects, likely due to the destruction of hair follicle units.