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This study suggests that the HCR risk allele within the PSORS1 locus may contribute to psoriasis susceptibility by altering gene expression related to skin structure and differentiation, although these changes alone might not result in clinical symptoms.

This review discusses advances in using molecular tools from skin biology to manipulate adult stem cells for regenerative medicine and reports no new clinical results.

This study found that the PSEN1-P242LfsX11 mutation in hidradenitis suppurativa influences cytokine and chemokine expression in macrophages, potentially affecting inflammatory responses.

This study found that Lymphotoxin-beta primarily influences periderm differentiation, impacting epidermal and hair follicle differentiation at later stages.

This study observed that erosive pustular dermatosis of the scalp in elderly patients was effectively treated with high-potency topical steroids, with plasma and lymphocyte dermal infiltrates helping to confirm diagnosis.

This study observed that women with PCOS have lower resistive and pulsatility index values in ovarian stromal arteries compared to normal women, indicating Doppler ultrasonography as an effective diagnostic tool for PCOS-related hemodynamic changes.

In this interventional therapeutic study, both intralesional triamcinolone acetonide and vitamin D3 showed significant improvement in alopecia areata, with terminal regrowth more frequently observed in the steroid group, although differences were not statistically significant.

In this retrospective cohort study, researchers found no significant difference between finasteride and dutasteride in terms of reducing prostate volume or adverse effects among patients with benign prostatic hyperplasia, although both drugs improved lower urinary tract symptoms over one year by reducing prostate volume.

This study found that moderate acne was the most common type among patients, with females predominantly affected, and highlighted that several factors, like seborrhea, were linked to acne severity.

This study mapped monilethrix, a hereditary hair and nail disorder, to the type II keratin cluster on chromosome 12q, marking the first primary human hair disorder localization and implicating defects in "hard" keratins.

This study found that SRD5a-3 is a highly efficient enzyme for converting hormones into androgens, with dutasteride being a much more potent inhibitor of SRD5a-3 than SRD5a-2.

This study found that long-term dutasteride therapy in men with benign prostatic hyperplasia worsened erectile dysfunction, reduced testosterone levels, and increased blood glucose and lipid profile, indicating negative metabolic impacts.

This study found that long-term finasteride therapy in men with BPH worsened erectile dysfunction and reduced testosterone levels, while these effects were not observed with tamsulosin.

This study found a high prevalence of hyperandrogenemia in women with PCOS, with distinct biochemical differences according to BMI and presence of hyperandrogenemia.

This report advances the hypothesis that finasteride and dutasteride inhibit 5α-reductase activities, potentially altering steroid metabolism and increasing the risk of insulin resistance, diabetes, and vascular disease.

This randomized clinical trial found that vitamin D supplementation did not significantly alter anthropometric or metabolic parameters in obese, insulin-resistant, and vitamin D-deficient women with polycystic ovary syndrome, whereas metformin effectively reduced body weight, BMI, waist circumference, total body fat, and serum glucose levels.

This study found that subclinical hypothyroidism had minimal impact on the metabolic and hormonal profiles of women with polycystic ovary syndrome.

This article reviews common hair loss disorders, emphasizing their potential links to systemic disease and the importance of thorough diagnostic evaluation, but reports no new clinical results.

This review discusses the pathogenesis of hirsutism and related diagnostic criteria for polycystic ovary syndrome in Korean women, but reports no new clinical results.

This study found that low-dose finasteride treatment in men with premature androgenetic alopecia decreased levels of 5α-reduced steroids, which may be linked to increased depression symptoms.

The authors suggest that scalp pain resulting from infestations, infections, or inflammatory diseases should be included in the next classification of headaches, as it currently lacks clear clinical characteristics and inclusion in the ICHD-3 criteria.

This case study reports intracranial hypertension in a 60-year-old woman linked to prolonged intake of low-dose Vitamin A from propolis capsules, highlighting a potential risk even at lower dosages.

This study found that certain plasma protein ratios, specifically AGRN/HSPG2 and DECR1/FKBP1B, were significantly associated with an increased risk of alopecia areata, indicating potential causal relationships but reverse causality was not supported.

This case report describes a patient's psychiatric and medical journey after a cardiac arrest, focusing on managing agitated behavior without medication, leading to significant improvement in cognitive function over a 5-week hospital stay.

This study developed a new analytical method to identify a wide range of endocrine disrupting compounds in full-term amniotic fluid, revealing diverse substances with potential endocrine activity.

This study suggests that the interaction between folliculin and plakophilin-4 (p0071) may play a role in folliculin's tumor suppressor function by regulating RhoA signaling, impacting cell migration and junction formation.

This review summarizes the role of platelet-rich plasma in treating musculoskeletal injuries in athletes, highlighting its current and potential applications, but it reports no new clinical findings.

The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.

In this review, dermatological symptoms associated with various eating disorders, such as anorexia nervosa, bulimia nervosa, binge eating disorder, and pica, were examined, highlighting the potential role of dermatologists and psychiatrists in early diagnosis and interdisciplinary treatment approaches.

This study reports that finasteride can effectively treat androgenic alopecia and may reduce prostate cancer risk by 25% in men with risk factors.