research Detection of Lentiviral Constructs for Release Testing of CAR-T Cells Using Digital Droplet PCR
The new ddPCR method reliably detects unwanted viruses in CAR-T cell products, ensuring their safety for patients.
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research Selling Stem Cells in Australia: Assessing the Impact of New Advertising Standards on Business Practices
New Australian advertising rules improved stem cell marketing practices but further regulation is needed for consumer safety.
research Analysis of Androgenetic Alopecia in Amerindian People (Mapuche) from Southern Chile
Androgenetic alopecia is less common in Chilean Mapuche than Caucasians, but more common than Asians, with racial differences in prevalence and types.
research Autologous Stem Cell-Based Interventions in Australia: Exploring Patient Experience in Light of Regulatory Exceptionalism
Patients in Australia underwent costly, unproven stem cell treatments due to weak regulations and aggressive marketing.
research Registrars’ Symposium: Summaries of Papers
Lower adrenal hormone levels may cause hair loss in postmenopausal women, certain patterns help diagnose nail cancer, and a gene variant linked to higher skin cancer risk in kidney transplant patients suggests monitoring folate levels.
research Severe Cutaneous Adverse Reactions to Drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research Cutaneous Lupus Erythematosus: A Review
Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
research Permanent Alopecia Following Chemotherapy and Bone Marrow Transplantation
Chemotherapy and bone marrow transplant can cause permanent hair loss.
research Vitiligo
Vitiligo causes white skin patches and is linked to autoimmune issues.
research Transcriptional Profiling in Alopecia Areata Defines Immune and Cell Cycle Control Related Genes Within Disease-Specific Signatures
The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
research Cutaneous and Mucosal Manifestations Associated with Celiac Disease
Celiac disease can cause skin problems that may get better with a gluten-free diet.
research Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency: Pathophysiology, Diagnosis, and Treatment
The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.
research Plasmacytoid Dendritic Cells in Alopecia Areata: Missing Link?
Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.
research Environmental Stress But Not Subjective Distress in Children or Adolescents With Alopecia Areata
Kids with alopecia areata may experience more stress but not necessarily feel more anxious or depressed than others.
research An Investigation of Vitamin D Status in Alopecia Areata
People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.
research The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target
Targeting CD200 could be a new treatment for rheumatoid arthritis.
research Nonclassic Congenital Adrenal Hyperplasia: Pathophysiology, Genetics, and Management
Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.
research The Pathogenesis of Alopecia Areata in Rodent Models
Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
research The Histopathology of Alopecia Areata in Vertical and Horizontal Sections
Horizontal scalp biopsy sections are better for diagnosing alopecia areata, showing fewer hair follicles and more miniaturized hairs.
research Review of Aseptic Neutrophilic Dermatoses
The review says skin conditions with sterile pustules need more research for better treatments.
research Pleuropericardial Effusion Associated With Minoxidil Administration
Minoxidil can cause pericardial and pleural effusions with high protein content.
research Signal Transducer and Activator of Transcription 5B Deficiency Due to a Novel Missense Mutation in the Coiled-Coil Domain
A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
research ACTH as First Line Treatment for Acute Calcium Pyrophosphate Crystal Arthritis in 14 Hospitalized Patients
ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.
research Mechanisms of Tolerance and Potential Therapeutic Interventions in Alopecia Areata
Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
research Multiple Myeloma-Associated Amyloidosis Presenting With Acrolocalized Acquired Cutis Laxa
A man with rare skin changes on his fingers was diagnosed with multiple myeloma-linked amyloidosis.
research Fatal Toxic Epidermal Necrolysis Associated With Minoxidil
Minoxidil can cause deadly skin reaction; monitor patients closely.
research Beau's Lines
Beau's lines and hair loss in a patient were linked to severe stress on the body.
research Diffuse Pattern Essential Syphilitic Alopecia: An Unusual Form of Secondary Syphilis
Syphilis can cause hair loss and should be considered in unexplained cases.
research Retinoids Putting the 'A' in Alopecia
Vitamin A may influence hair loss conditions like alopecia, but more research is needed to understand how.
research Apremilast and Tofacitinib Exert Differential Effects in the Humanized Mouse Model of Alopecia Areata
Tofacitinib was more effective than apremilast in treating hair loss in a mouse model of alopecia areata.