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Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Telocytes might help with skin repair and regeneration.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.