9 citations
,
July 2020 in “Journal of Dermatology” This study found that diffuse and pseudo-fringe sign patterns are common in Asian patients with frontal fibrosing alopecia, and that treatments combining antiandrogens or antimalarials with topical therapy are effective.
1 citations
,
June 2024 in “European Journal of Dentistry” This study found that human placenta extract may be a promising pulp-capping material, causing less intense chronic inflammation and thicker dentine bridge formation compared to mineral trioxide aggregate in dogs' teeth.
February 2026 in “Frontiers in Medicine” This study found that fibrosing alopecia in a pattern distribution in Hispanic male patients often resembles androgenetic alopecia, with a tendency for earlier onset compared to European and North American populations.
10 citations
,
May 2018 in “Cell death discovery” This study found that the interaction between heat shock protein 90 and lamin A/C is crucial for the growth, migration, and self-aggregation of dermal papilla cells, suggesting a potential role in alopecia areata mechanisms.
34 citations
,
February 2012 in “Journal of Cutaneous Pathology” This research retrospectively evaluated 92 skin specimens to propose histopathological criteria for diagnosing alopecia areata incognito, distinguishing it from telogen effluvium and androgenetic alopecia.
170 citations
,
December 2009 in “Histopathology” This review discusses the histopathological diagnosis of scarring and non-scarring alopecias, emphasizing the importance of adequate tissue sampling and clinical information; it reports no new empirical results.
111 citations
,
November 2007 in “Clinics in Dermatology” This article discusses the histologic features of psoriasis, including psoriasiform epidermal hyperplasia and neutrophilic involvement, but reports no new clinical findings.
90 citations
,
June 2006 in “The American Journal of Dermatopathology” This review outlines the classification, histopathologic presentation, and pathogenetic concepts of scarring and nonscarring alopecias, reporting no new clinical results and emphasizing the need for clinicopathologic correlation.
27 citations
,
July 2013 in “Journal of Dermatological Science” The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.
16 citations
,
November 2013 in “European Journal of Dermatology” In this study, researchers characterized the normal scalp hair properties in South Koreans, observing that hair density declined with age and varied across scalp sites, while hair thickness patterns remained relatively stable until later in life.
5 citations
,
August 2020 in “Curēus” This review systematically analyzed literature to differentiate desmoplastic trichoepitheliomas from other cutaneous tumors based on clinical, histopathological, and immunohistochemical features but reports no new clinical results.
5 citations
,
June 2019 in “Dermatopathology” This study found poor agreement among dermatopathologists in identifying and grading fibrosis in traction alopecia, suggesting the need for better diagnostic methods for early fibrosis detection.
1 citations
,
October 2024 in “Dermatology Practical & Conceptual” This study suggests that RCM may be a promising non-invasive diagnostic tool for alopecia areata incognita, showing substantial agreement with histopathology while noting some discrepancies.
The researchers observed that in cases of alopecia areata with atypical features, histopathological confirmation may be necessary, as trichoscopic clues like loss of follicle ostia and vellus hairs were common, while typical features such as exclamation mark hairs were not always present.
May 2023 in “Tạp chí Da liễu học Việt Nam” This study involving Vietnamese patients with alopecia areata found that histopathological examination is crucial for diagnosis, noting diverse features including peribulbar lymphocytic infiltration and varying hair follicle characteristics across disease stages, with eosinophils and necrosis observed in some cases.
April 2016 in “Journal of The American Academy of Dermatology” Certain scalp tissue features can predict how well alopecia areata responds to steroid injections.
9 citations
,
August 2014 in “The Journal of Dermatology” This study found that clinically non-affected perilesional scalp in Japanese alopecia patients often showed microscopic abnormalities, which may help in assessing the spread of disease activities.
52 citations
,
December 2000 in “Archives of Dermatological Research” This study found that the stratum corneum of scalp skin in humans has distinct functional characteristics compared to the facial skin and volar forearm, including higher hydration levels and intermediate epidermal turnover rates.
26 citations
,
September 2012 in “Journal of The American Academy of Dermatology” This study observed that patients with rapidly progressive alopecia areata may have a favorable prognosis regardless of treatment, and regenerated vellus hairs were linked to higher improvement or cure rates.
24 citations
,
November 2021 in “PLoS ONE” In this study, fractional laser treatment was observed to reverse age-related gene expression changes in skin and enhance dermal remodeling, further improved by multiple treatments.
20 citations
,
June 2019 in “Experimental Dermatology” This study identified 14 genes affected by copy number variants that may contribute to alopecia areata, including four genes notably involved in autophagy and chromatin remodeling.
13 citations
,
August 1995 in “Australasian Journal of Dermatology” This study found that hair canal and follicle diameters, outer root sheath area, and terminal-to-vellus hair ratios were significantly reduced in androgenetic alopecia patients compared to normal controls.
8 citations
,
August 2014 in “Clinical and Experimental Dermatology” This study found that chronic telogen effluvium is a distinct condition from female pattern hair loss, with different pathogenic mechanisms observed in histomorphometric analyses.
6 citations
,
January 2017 in “Journal of toxicologic pathology” This study suggests that the patchy thickening and reddish discoloration in rabbit skin during the hair cycle may be due to large anagen-phase hair follicles compressing the dermis and increased blood vessels causing redness.
5 citations
,
February 2015 in “Journal of Comparative Pathology” This study suggests that high proliferative activity and peripheral invasion are key indicators of malignancy in canine sebaceous gland tumours. It also reports a higher incidence of circumanal gland and testicular tumours, indicating a possible androgen-related pathway in tumour development.
1 citations
,
September 2011 in “UHOD : Uluslararası hematoloji - onkoloji dergisi” This study found no significant differences in age, sex, or histopathological characteristics for differentiating basal cell carcinoma from benign tumors of cutaneous appendages, complicating diagnosis.
December 2023 in “Pakistan Journal of Medical & Health Sciences” This study found that in South Asian women with PCOS, the severity of non-alcoholic fatty liver disease is strongly linked to early renal dysfunction, as indicated by increased serum creatinine and urinary albumin levels, and reduced eGFR.
This study found a significant discordance between clinical symptoms and dermatoscopic signs with histopathological inflammation in patients with LPP and AFF, affecting diagnostic and therapeutic approaches.
August 2021 in “Annals of pathology and laboratory medicine” This study observed that benign skin tumors were more common than malignant ones, with squamous cell carcinoma being the most frequent type among malignant tumors.
1 citations
,
January 2020 in “Skin appendage disorders” This study questions whether lymphocytic infiltrate and fibrosis observed after uncomplicated hair transplants might be expected without indicating lichen planopilaris.