research The Pioneer Factor SOX9 Competes for Epigenetic Factors to Switch Stem Cell Fates
SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
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research Tailored Chromatin Modulation to Promote Tissue Regeneration
Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
research Novel Advances of Histone Modification in Inflammatory Skin Diseases and Related Treatment Methods
Histone modification is key in treating chronic inflammatory skin diseases.
research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets
Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research DNA Methylation as an Epigenetic Memory Keeper During Skin Development and Regeneration
DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
research Tracing the Cellular Origin of Cancer
Understanding where cancer cells come from helps create better prevention and treatment methods.
research ATP-Dependent Chromatin Remodeling During Mammalian Development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research The Role of Androgen and Androgen Receptor in Skin-Related Disorders
Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
research An Integrative View of Mammalian Seasonal Neuroendocrinology
The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
research Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris
Topical therapies show promise for hair loss and acne treatment with minimal side effects.
research Developmental Plasticity of Patterned and Regenerating Oral Organs
Fish teeth and taste bud densities are linked and can change between types due to shared genetic and molecular factors.
research Androgen Effects on the Skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research A Hairy Situation: PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
research Vitamin D: More Than a Bona Fide Hormone
Vitamin D is important for bones, hair, blood pressure, and breast development.
research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Wnt signaling is crucial for skin development and hair growth.
research Premature Aging Syndromes: From Patients to Mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research The 1,25-Dihydroxyvitamin D3-Independent Actions of the Vitamin D Receptor in Skin
The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.
research Resident Macrophages of the Lung and Liver: The Guardians of Our Tissues
Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
research MOF-Mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions by Controlling Gene Promoters
MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.
research Genome-Wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage
Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
research MOF-Mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions by Controlling Gene Promoters
MOF controls skin development by regulating genes for mitochondria and cilia.
research Epigenetic Control of Adult Stem Cell Function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research Roles of Jumonji and Jumonji Family Genes in Chromatin Regulation and Development
Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
research Inhibition of Class I HDACs Preserves Hair Follicle Inductivity in Postnatal Dermal Cells
Inhibiting class I HDACs helps maintain hair growth ability in skin cells.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Epigenetics of Colorectal Cancer
Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
research Morpho-Regulation in Diverse Chicken Feather Formation: Integrating Branching Modules and Sex Hormone-Dependent Morpho-Regulatory Modules
Sex hormones, especially estradiol, can change chicken feather shapes and colors.
research Fatal Autoimmunity Results from the Conditional Deletion of Snai2 and Snai3
Deleting Snai2 and Snai3 causes fatal autoimmunity.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.