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Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Polycomb Repressive Complex 2 is not needed for hair regeneration.

Acid inside cells speeds up aging and turns on aging signs in mice.

Light and temperature affect the daily skin function rhythms in hairless rats, with temperature influencing water loss but not skin hydration.

Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.

Age-related hair loss is linked to the decline and dysfunction of hair follicle stem cells.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

DNA methylation changes are linked to hair growth cycles in goats.

Patients using social media have mixed feelings about alopecia treatments, noting hair growth but also frustration with treatment recurrence.

Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.

Some Greek melanoma patients have gene mutations linked to increased cancer risk, a new color feature helps diagnose melanoma, the incidence of a skin condition in the Netherlands is rare, and a gene possibly affects male-pattern baldness.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.