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Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Apremilast may help treat hair loss in alopecia areata.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Non-coding RNAs could help detect and treat radiation damage.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Notch signaling disruptions can cause various skin diseases.

Chrysin makes docetaxel more effective and reduces its side effects in lung cancer treatment.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

Activating Notch signaling can kill basal cell carcinoma cells.

TLR4 is important in aging-related diseases and could be a new treatment target.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

SOX9 is essential for the development of various organs and hair follicles.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Blocking YAP/TAZ could be a new way to treat skin cancer.

New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Natural skincare products may help reduce sun damage and support the skin's daily cycle.