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The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Testosterone may slow down wound healing and increase inflammation.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.

Phosphatidic acid may help hair grow by affecting cell growth pathways.