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Acid inside cells speeds up aging and turns on aging signs in mice.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

SET7/9 enzyme affects cell growth and diseases like cancer, diabetes, and obesity.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.

Diet changes can protect against harmful environmental effects on fetal development.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

Topical valproate can effectively promote hair growth.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Testosterone may slow down wound healing and increase inflammation.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Hair proteins have weak spots in their α-helical segments.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.