20 citations
,
February 1968 in “Journal of Histochemistry & Cytochemistry” This study reports that citrulline, uniquely found in the inner root sheath of hair follicles, can be specifically detected with the carbamido diacetyl reaction, resulting in a bright orange color.
9 citations
,
November 2009 in “Journal of the European Academy of Dermatology and Venereology” This study found that serial vertical sectioning of scalp biopsies significantly increases the histological diagnostic yield for alopecias.
2 citations
,
March 2019 in “Lasers in surgery and medicine” This study found that human hair follicles demonstrated a dose-dependent response to light in an ex vivo photoepilation model, which could predict the clinical efficacy and permanency of light-based hair removal devices.
In this research, low-fluence light-based hair removal was explored, revealing its potential for at-home use with improvements in efficacy and safety, particularly for dark skin individuals, although further studies are necessary.
26 citations
,
April 2011 in “Skin Research and Technology” This study found that in vivo confocal scanning laser microscopy accurately quantifies neogenic hair follicles in mice, producing results similar to histology while avoiding fixation artifacts.
4 citations
,
October 2012 in “Archives of Dermatology” Hair diameter diversity is a key sign for diagnosing and managing male pattern baldness.
January 2008 in “Chinese Journal of Aesthetic and Plastic Surgery” In this study, the authors found that rabbit hair material ground for 8 hours had better suitability and histocompatibility for injectable soft tissue augmentation compared to other tested formulations.
116 citations
,
January 1957 in “Australian Journal of Agricultural Research” This study analyzed skin specimens from Australian Merino ewes to estimate hair follicle properties across different strains, providing baseline data essential for future genetic studies on fleece structure, but reported no new conclusions.
23 citations
,
July 1982 in “International Journal of Dermatology” The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.
5 citations
,
January 2019 in “Methods in molecular biology” In this study, researchers showed that multiphoton microscopy with fluorescent protein tagging enables single-cell imaging and tracking in live transgenic mice, offering new insights into cell dynamics in stem cell research compared to traditional histological methods.
5 citations
,
February 2011 in “Expert Opinion on Drug Discovery” This review discusses techniques and models for assessing hair growth activity but reports no new clinical findings, emphasizing the need for standardization and improved animal models.
19 citations
,
October 2014 in “Veterinary Dermatology” Dermoscopy is a good, noninvasive way to see normal cat skin structures and could be useful for check-ups.
12 citations
,
July 2017 in “Journal of cosmetic dermatology” This study suggests that infrared thermography may be a useful noninvasive tool for diagnosing active phases of frontal fibrosing alopecia when combined with dermoscopy.
7 citations
,
January 2003 in “Journal of cosmetic and laser therapy” This study concluded that the Spa Touch system effectively retards hair regrowth, functioning like a "light razor" for quick and cost-effective epilation.
October 2024 in “Experimental Dermatology” This study examined hair follicles from 14 Caucasian males and found that catagen-phase follicles were more prevalent (7.5%) than previously reported, challenging the established view that telogen-phase follicles are more common.
January 2022 in “Przegla̧d dermatologiczny” This article reviews various treatment options for diseases associated with cicatricial alopecia but reports no new clinical results.
October 2021 in “Journal of the European Academy of Dermatology and Venereology” This review discusses the significant progress in the diagnosis and treatment of hair loss disorders over the last 30 years and reports no new clinical results.
April 2017 in “Journal of Investigative Dermatology” This study observed that a 3D culture model of hair follicle cells showed an anagen-like phase between days 3 to 6 and transitioned to a catagen-like phase by day 7, highlighting cell differentiation and structural development over time.
20 citations
,
November 1989 in “PubMed” This case report highlights that diagnosing fungal skin infections in immunocompromised patients requires culture for accurate identification, as histologic findings alone can be misleading.
17 citations
,
September 2012 in “Dermatologic Clinics” This review discusses histologic findings in alopecia and emphasizes the importance of understanding normal follicular anatomy and cycles in transverse sections, without reporting new results.
29 citations
,
June 2013 in “Journal of the Saudi Society of Dermatology & Dermatologic Surgery” This review outlines the mechanisms, clinical features, and management strategies for alopecia areata and presents no new experimental findings.
This study reviewed and reclassified 37 cases of primary scarring alopecia using histological methods to achieve more accurate diagnoses within subtypes like lupus erythematosus and lichen planopilaris.
59 citations
,
June 2008 in “Journal of The American Academy of Dermatology” This article reviews major types of genetic hair shaft defects and associated syndromes, emphasizing understanding histologic features and diagnostic methods, but reports no new clinical findings.
April 2026 in “Scientific Reports” In this study, the proposed MSF-VMDNet, combining dual encoder networks with a multi-frequency domain mechanism, significantly outperformed existing methods in segmenting skin cancer tissues from histological slide images, achieving high accuracy with an MIoU of 95.37% and a Dice coefficient of 95.11%.
3 citations
,
October 2022 in “PloS one” This study developed a method to culture and maintain chicken feather follicles in vitro, preserving structure and biology similar to their in vivo state, though some gene expression was altered.
1 citations
,
November 2014 in “Journal of Biomedical Optics” This study introduced a noninvasive spectroscopy method to assess hair follicle stages in mice by measuring skin diffuse reflectance and melanin dynamics, offering a potential tool for hair regeneration research.
This review discusses various non-invasive methods for diagnosing alopecia areata, highlighting that trichoscopy signs like short vellus hairs and yellow dots are sensitive indicators of the condition, while advanced imaging techniques provide valuable information on hair follicle status and scalp inflammation.
1 citations
,
July 2014 in “Our Dermatology Online” This article describes a rare case of alopecia with both scarring and non-scarring features, combining histologic signs of central centrifugal cicatricial alopecia with select immunologic features of alopecia areata.
April 2023 in “Journal of Investigative Dermatology” In this study, trypsin digestion was found to be a faster and more efficient method than the explant technique for extracting bulge-derived keratinocytes from adult scalp biopsies.
153 citations
,
August 2002 in “Dermatologic Surgery” This paper introduces the Follicular Unit Extraction procedure and its accompanying FOX Test, finding that 60% of tested patients were suitable candidates for this minimally invasive hair transplantation method.