42 citations,
June 2019 in “Aging” 3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.
40 citations,
July 2015 in “Kidney International” IL-3 worsens lupus nephritis and blocking it improves kidney health.
39 citations,
September 2007 in “BMC developmental biology” Neuregulin3 affects cell development in the skin and mammary glands.
36 citations,
January 2015 in “Clinical and Translational Allergy” Humans and pets share similar allergy mechanisms, and studying pet allergies can help treat both human and animal allergies.
35 citations,
December 2020 in “International Journal of Molecular Sciences” Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
34 citations,
February 2015 in “Frontiers in Cellular Neuroscience” Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.
28 citations,
September 2021 in “EMBO reports” Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
26 citations,
February 2015 in “Pediatric blood & cancer” Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.
24 citations,
July 2019 in “Reproductive Medicine and Biology” The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.
24 citations,
November 2015 in “International Journal of Cosmetic Science” Treating scalp issues with anti-dandruff shampoo improves hair health.
22 citations,
August 2021 in “Frontiers in medicine” Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.
22 citations,
January 2014 in “Journal of Interferon & Cytokine Research” Certain genetic variations in IL18 may increase the risk of alopecia areata in Koreans.
22 citations,
January 2012 in “Mediators of inflammation” Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
21 citations,
June 2022 in “Molecules” Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
19 citations,
July 2020 in “EBioMedicine” A gene variant increases the risk of a type of hair loss by affecting hair protein production.
18 citations,
October 2020 in “Radiation Research” Some drugs may help treat both COVID-19 and radiation injury.
18 citations,
June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
16 citations,
January 2022 in “International journal of molecular sciences” Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.
15 citations,
October 2021 in “Frontiers in Pharmacology” Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
15 citations,
June 2019 in “Experimental Dermatology” Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.
15 citations,
April 2008 in “Headache” People with migraines often have mental health conditions, and treatment should be personalized to address both issues safely.
14 citations,
September 2021 in “International journal of molecular sciences” Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.
14 citations,
August 2021 in “Molecular Genetics and Metabolism Reports” Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.
11 citations,
August 2023 in “Burns” Nerve growth factor helps improve healing time and scar quality in burn wounds.
11 citations,
July 2012 in “Experimental dermatology” Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
10 citations,
September 2022 in “Journal of Biophotonics” Blue light therapy is safe for skin and may protect against UV radiation.
10 citations,
July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
10 citations,
July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
9 citations,
November 2022 in “Applied sciences” Marine algae compounds may improve skin health and promote hair growth.
9 citations,
January 2022 in “Biology” Male mice are more susceptible to autism-like changes from valproic acid than female mice.