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This integrative literature review found that hydroxychloroquine may stabilize inflammatory scarring autoimmune alopecias like frontal fibrosing alopecia, especially when combined with other therapies, while its effectiveness in non-scarring alopecias appears inconsistent and is limited to refractory cases.

Testosterone, 4-hydroxyandrostenedione, and finasteride affect blood clotting differently in stressed heart conditions.

This study reported that introducing the TERT and Bmi1 genes into mouse dermal papilla cells resulted in immortal cells capable of inducing new hair follicles in vivo, and human immortal DPCs were also developed.

This study found that after four weeks of daily use, the roughness of the hair surface significantly decreased, as shown through quantitative image analysis using HIROX.

This study found that the use of high pH chemical agents for hair straightening can cause significant damage to hair, including protein degradation and weakened fiber strength, and may lead to permanent scalp conditions like contact dermatitis and cicatricial alopecia.

Vitiligo and alopecia areata might be early signs of Type 1 Diabetes.

In this study, γ-ray irradiation of mice reduced hair follicle density and pigmentation, suggesting damage to stem cells and progenitors for keratinocytes and melanocytes.

This study found that Phyllanthus urinaria extract displayed significant anti-alopecia properties in a mouse model, showing potential as an anti-5α-reductase agent for androgenic hair loss.

This study found that the BIK1 gene in Arabidopsis thaliana modulates defense responses to pathogens and is essential for normal root growth and development.

COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.

This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.

This review discusses human sebocyte in vitro models for studying sebaceous gland function and control but reports no new clinical results, highlighting hormonal effects and the impact of retinoids on sebocyte activity.

This review compares animal and human skin characteristics in in vitro permeation studies but reports no new results, highlighting variations and the need for better model correlations.

This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.

This study identified gene expression patterns in a mouse model that may influence tumor susceptibility and tissue functions related to inflammation and cell proliferation, highlighting Lgr5 and the vitamin D receptor as key regulators.

This study found that hair follicles in both mice and humans may serve as an important site for melatonin synthesis and signaling, potentially influencing hair cycle regulation by modulating keratinocyte apoptosis.

In this study, oral administration of Lactococcus lactis strain H61 to senescence-accelerated mice was linked to reduced bone density loss, less skin ulcer incidence, and reduced hair loss, along with altered immune responses.

A specific gene mutation causes woolly hair and hair loss.

This study describes Hg(OTf)2 as a new and efficient catalyst for various organic synthesis reactions, including alkyne hydration and C–C bond forming cyclizations.

This study found that beta-caryophyllene enhanced re-epithelialization in cutaneous wounds of female mice, suggesting its potential for improving wound healing through multiple pathways.

This study found that nanoparticles did not permeate intact rat skin but could penetrate skin that had been artificially punctured, primarily through grooves or hair follicles.

This study demonstrated that bioengineered hair follicles reconstituted from embryonic skin cells and transplanted into hosts can restore physiological hair functions, suggesting potential applications for treating alopecia.

This study found that the ethanol patch test effectively indicates the ALDH phenotype in healthy Japanese individuals, suggesting its usefulness for future research.

This study suggests that hairlessness in nude mice may be due to insufficient expression of phospholipase C-δ1, a molecule essential for normal hair development downstream of the Foxn1 gene.

This study identified a mutation hotspot in the caracul (Ca) locus of mice, implicating the mK6irs1/Krt2-6g gene in hair formation and potentially human hair and skin diseases.

This study found that KRTAP2 proteins predominantly express in the hair shaft cortex of humans, interact with hair keratins, and play crucial roles in hair shaft keratinization.

This study demonstrated that combining AMD3100 with low-dose tacrolimus in a stem cell mobilization approach significantly reduced wound healing time and improved scar and hair follicle regeneration in full-thickness skin wounds.

Merkel cells are abundant in facial vellus hair follicles, especially during the anagen phase.

This study found that treatment with the polyphenolic compound TCQA activated β-catenin, promoting hair regrowth and the initiation of the anagen phase in mice and human dermal papilla cells.