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TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Some common medications can harm male fertility, but many effects can be reversed.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Men and women react differently to opioids, with hormones potentially influencing these differences.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.

Researchers found two new genetic variants linked to Alzheimer's disease.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Immune cells are essential for early hair and skin development and healing.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Long COVID causes various long-term health issues and needs better awareness and treatment.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.