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Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Androgens can help prevent memory problems caused by apoE4.

Stem cell niches support, regulate, and coordinate stem cell functions.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Certain genes control the color of human hair by affecting pigment production.

The circadian clock influences the behavior and regeneration of stem cells in the body.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

*Acorus calamus* has many medicinal benefits but needs more safety research.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.