research Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss
Aromatase gene variation may increase female hair loss risk.
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research High-Throughput Phenotyping Methods for Quantifying Hair Fiber Morphology
Quantifying hair shape is better than using racial categories for understanding hair characteristics.
research Small Molecules and Small Molecule Drugs in Regenerative Medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
research Pyrene Excimer Nucleic Acid Probes for Biomolecule Signaling
Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.
research How Different Is Human Hair? A Critical Appraisal of Global Hair Fibre Characteristics and Properties Towards Defining a More Relevant Framework for Hair Type Classification
Human hair varies widely and should be classified by curl type rather than race.
research Melatonin Modulates Tomato Root Morphology by Regulating Key Genes and Endogenous Hormones
Melatonin improves tomato root growth and plant health at certain levels by affecting genes and hormones but can damage roots at high levels.
research Glycome Profiling by Lectin Microarray Reveals Dynamic Glycan Alterations During Epidermal Stem Cell Aging
Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.
research Emerging Diagnostic and Therapeutic Potentials of Human Hair Proteomics
Hair protein analysis could improve medical testing and understanding of hair characteristics.
research New Frontiers in CRISPR/Cas9 Delivery Systems for Gene Editing
Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.
research The Opportunities and Challenges Regarding Induced Platelets from Human Pluripotent Stem Cells
Human pluripotent stem cells could be used to make platelets for medical use, but safety, effectiveness, and cost issues need to be resolved.
research Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents
Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Human Gene Correlation Analysis: A Tool for the Identification of Transcriptionally Co-Expressed Genes
The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
research Improving Selective Androgen Receptor Modulator Discovery and Preclinical Evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Ameliorative Effects of Rutin Against Metabolic, Biochemical, and Hormonal Disturbances in Polycystic Ovary Syndrome in Rats
Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
research Redefining Hormone Resistance in Prostate Cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Prediction of Male-Pattern Baldness from Genotypes
Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.
research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS
The method can measure vitamin B3 levels in human hair accurately.
research Three-Dimensional Reconstructions of Mechanosensory End Organs Suggest a Unifying Mechanism Underlying Dynamic, Light Touch
Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.
research Colon Cancer Stem Cells: Promise of Targeted Therapy
Targeting colon cancer stem cells might lead to better treatment results.
research Cartilage to Bone Transformation During Fracture Healing Is Coordinated by the Invading Vasculature and Induction of the Core Pluripotency Genes
Blood vessels and specific genes help turn cartilage into bone when bones heal.
research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study
research Sex Differences in COVID-19: The Role of Androgens in Disease Severity and Progression
Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Finasteride Use in the Male Infertility Population: Effects on Semen and Hormone Parameters
Finasteride can reduce fertility in some men, but stopping it increases sperm count.
research Advances in Nucleoside Monophosphate Prodrugs as Anti-HCV Agents
New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.
research Trichodysplasia of Immunosuppression Treated with Oral Valganciclovir
Oral valganciclovir improved a patient's skin condition caused by immunosuppression.