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Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Herbal nano-formulations show potential for effective skin delivery but need more research.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.

COVID-19 can cause various skin issues, including rashes and hair loss, which usually heal on their own and don't always indicate severe illness.

Mutations in certain receptors can cause diseases and offer new treatment options.

Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Stem cells can rejuvenate skin, restore hair, and aid in wound healing.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

People with Lichen planopilaris are more likely to have certain autoimmune and endocrine disorders but less likely to have conditions like allergies and diabetes.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

Graying hair happens due to aging and might be delayed by new treatments.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Women experience various skin issues at different life stages, requiring careful treatment and awareness.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.