research Noncoding dsRNA Induces Retinoic Acid Synthesis to Stimulate Hair Follicle Regeneration via TLR3
Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
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research The Human Gut Chemical Landscape Predicts Microbe-Mediated Biotransformation of Foods and Drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research Variation in Human Hair Ultrastructure Among Three Biogeographic Populations
Different populations have distinct hair structures related to their ancestry.
research Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men
Finasteride can cause sexual problems and depression in young men.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Alcohol Exposure During Late Adolescence Increases Drinking in Adult Wistar Rats, an Effect That Is Not Reduced by Finasteride
Alcohol in teen years leads to more adult drinking, finasteride doesn't help.
research Structure of Intermediate Filament Assembly in Hair Deduced from Hydration Studies Using Small-Angle Neutron Scattering
Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.
research Mechanism of Cuticle Hole Development in Human Hair Due to UV Radiation Exposure
UV radiation damages hair by creating holes and peeling cuticle layers.
research Keratin-Mediated Hair Growth and Its Underlying Biological Mechanism
Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
research The Role of Androgens in Hormone Replacement Therapy
Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
research Protein Kinase C Is a Key Target for Attenuation of Leigh Syndrome by Rapamycin
Rapamycin may help treat Leigh syndrome by targeting protein kinase C.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research Dianabol Unveiled: A Systematic Review of Methandrostenolone
Dianabol boosts muscle growth but has serious health risks and legal issues.
research Exploring the Effects of Wetting and Free Fatty Acid Deposition on a Hair Fiber Surface Model Incorporating Keratin Associated Protein 5-1
Water and fatty acids affect hair's surface differently based on hair damage, and models can help understand hair-cosmetic interactions.
research Is Dehydroepiandrosterone a Hormone?
Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
research Epidemiology, Diagnosis, and Management of Hirsutism: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome Society
Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.
research Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair
Fat cells in the skin help start healing and form important repair cells after injury.
research Advanced Nanocarrier- and Microneedle-Based Transdermal Drug Delivery Strategies for Skin Diseases Treatment
Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
research Role of Anticonvulsant and Antiepileptogenic Neurosteroids in the Pathophysiology and Treatment of Epilepsy
Neurosteroids show promise for treating epilepsy and more research is needed.
research Self-Assembled Polymeric Nanocarriers for the Targeted Delivery of Retinoic Acid to the Hair Follicle
The new micelle formulation delivers acne treatment more effectively and safely than current gels.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Effect of Varied Hair Protein Fractions on the Gel Properties of Keratin/Chitosan Hydrogels for Use in Tissue Engineering
Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.
research Normal Fur Development and Sebum Production Depend on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands
FA2H is essential for normal fur and sebum production in mice.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research A Rational Approach to the Diagnosis of Polycystic Ovarian Syndrome During Adolescence
Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.
research A Guide to Studying Human Dermal Adipocytes In Situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
research Structural and Dynamic Insights into Substrate Binding and Catalysis of Human Lipocalin Prostaglandin D Synthase
The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.
research A Stability-Indicating HPLC Method to Determine Finasteride in a Tablet Formulation
New method quickly and accurately measures finasteride in tablets.
research Engineering Cell-Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.