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Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.

Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Premature graying of hair is linked to various health issues and can sometimes be reversed by treating underlying conditions.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

The guidelines help doctors diagnose and treat hormone-related disorders in women.

The document concludes that more research is needed to fully understand the causes of PCOS.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Some medications caused temporary health issues that improved after stopping the drugs, but two patients died from liver problems linked to carbamazepine.

Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.

Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.

Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.

Hair keratin-associated proteins are essential for strong hair, with over 80 genes showing specific patterns and variations among people.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.

The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

Successful hair transplant surgery depends on careful patient selection, proper surgical plan and technique, and attentive aftercare.

Free tissue transfer is highly effective for fixing exposed implants after skull surgery.

The document suggests using natural remedies like bloodletting and honey for various health issues but lacks scientific evidence for their effectiveness.

Metformin may help regulate periods and cause modest weight loss in PCOS patients, but more research is needed.

The most effective treatments for hair loss are minoxidil, finasteride, PRP, and hair transplants, with steroids and immunosuppressants for autoimmune types.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.